Author

J. A. Bittker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Organism:human· 1

Frequent Co-Authors

A. A. Tang· 1 shared A. Subramanian· 1 shared A. Tsherniak· 1 shared B. T. Wong· 1 shared C. C. Mader· 1 shared C. Mulrooney· 1 shared D. Peck· 1 shared E. Comer· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. A. Tang

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2 papers

Recent·Most cited

Non-oncology drugs are a source of previously unappreciated anti-cancer activity

S. M. Corsello, R. T. Nagari, R. D. Spangler, J. Rossen, M. Kocak, J. G. Bryan, R. Humeidi, D. Peck, X. Wu, A. A. Tang, V. M. Wang, S. A. Bender, E. Lemire, R. Narayan, P. Montgomery, , T. R. Golub

The paper identifies non-oncology drugs with anti-cancer activity across 578 cancer cell lines using PRISM, finding that many drugs selectively inhibit cancer cells based on molecular features.

bioRxiv · Aug 9, 2019Cancer Biology

High throughput screen identifies IFN-γ-dependent inhibitors of Toxoplasma gondii growth

J. B. Radke, K. L. Carey, S. Shaw, S. R. Metkar, C. Mulrooney, J. P. Gale, J. A. Bittker, R. Hilgraf, E. Comer, S. L. Schreiber, H. W. Virgin, J. R. Perez, L. D. D. Sibley

This study identifies IFN-γ-dependent inhibitors of Toxoplasma gondii growth through a high-throughput screen and characterizes their mechanisms of action.

bioRxiv · Jun 2, 2018Microbiology