IFITM3 regulates virus-induced inflammatory cytokine production by titrating Nogo-B orchestration of TLR responses
M. Clement, J. L. Forbester, M. Marsden, P. Sabberwal, D. Wellington, S. Dimonte, K. Harcourt, S. Clare, Z. Yin, L. Nobre, R. Antrobus, B. Jin, M. Chen, S. Makvandi-Nejad, J. A. Lindborg, , I. Humphreys
This study shows IFITM3 limits viral pathogenesis by regulating Nogo-B-mediated TLR responses and cytokine production in dendritic cells.
bioRxiv · Jul 23, 2021 · PreprintImmunology