Author

J. A. Porco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

L. E. Brown· 2 shared A. B. Beeler· 1 shared A. R. Ivanov· 1 shared B. Bhattacharya· 1 shared C. A. Iacobuzio-Donahue· 1 shared D. Kelsen· 1 shared D. Lyden· 1 shared D. Tuveson· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

L. E. Brown

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 18, 2021

BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking CLU+ CAF expression with HSF1 signaling

L. Shaashua, M. Pevsner-Fischer, G. Friedman…·R. Scherz-Shouval

This study shows BRCA mutations in pancreatic cancer alter CAF subtypes, specifically increasing CLU+ CAFs, and links this to HSF1 signaling.

DOI 10.1101/2021.08.18.456576

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintAug 31, 2020

Channeling macrophage polarization via selective translation inhibition by rocaglates increases macrophage resistance to Mycobacterium tuberculosis

S. Chatterjee, S. M. Yabaji, B. Bhattacharya…·I. Kramnik

This study shows rocaglates shift macrophage polarization toward M1-like by inhibiting IL-4 response and enhancing resistance to Mycobacterium tuberculosis.

DOI 10.1101/691808

humanbulk RNA-seq

𝕏 PostBluesky