Author

J. A. Seidel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

W. Zhang· 2 shared D. Gu· 1 shared F. Hu· 1 shared N. A. Zill· 1 shared S. Bhattarai-Kline· 1 shared S. Marinkovich· 1 shared S.-J. Kim· 1 shared W. Cai· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

W. Zhang

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2 papers

Recent·Most cited

Bioactive Natural Product Discovery via Deuterium Adduct Bioactivity Screening

N. A. Zill, Y. Du, S. Marinkovich, D. Gu, J. A. Seidel, W. Zhang

This paper introduces DABS, a new workflow for natural product discovery that combines isotope labeling with whole cell binding assays, leading to the identification of zillamycin with anti-cancer and anti-microbial activities.

bioRxiv · Mar 16, 2023 · PreprintMicrobiology

Live-cell Imaging Analysis of Antimycin-Type Depsipeptides via Bioorthogonal Stimulated Raman Scattering Microscopy

J. A. Seidel, Y. Miao, W. Porterfield, W. Cai, X. Zhu, S.-J. Kim, F. Hu, S. Bhattarai-Kline, W. Min, W. Zhang

This study uses bioorthogonal SRS microscopy to analyze the intracellular distribution of antimycin-type depsipeptides in living cells, showing their enrichment depends on potency, protein targets, and lipophilicity.

bioRxiv · Mar 21, 2019 · PreprintBioengineering