Author

S.-J. Kim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6 Bioengineering· 2 Plant Biology· 2 Biochemistry· 1 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 12 Research Focus:cell type annotation· 6 Research Focus:host-pathogen & immune response· 4 Assay:metagenomics· 4 Assay:proteomics· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:differential expression· 3 Organism:human· 3

Frequent Co-Authors

C. Wang· 2 shared D.-G. Ahn· 2 shared G. U. Jeong· 2 shared G. Y. Yoon· 2 shared H. J. Choi· 2 shared H. W. Moon· 2 shared K. Lee· 2 shared K.-D. Kim· 2 shared

Activity by Year

2017-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersBioengineering

C. Wang

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Author profile →

16 papers

Recent·Most cited

Unraveling membrane protein localization and stabilization in nanodiscs

S.-J. Kim, Y. H. Koh, S.-H. Roh

This study examines cryo-EM structures of membrane proteins in nanodiscs, revealing spatial preferences and direct interactions with MSPs that stabilize proteins.

bioRxiv · Jul 20, 2023 · PreprintBiophysics

Periodontitis promotes bacterial extracellular vesicle-induced neuroinflammation in the brain and trigeminal ganglion

J. Y. Ha, J. Seok, S.-J. Kim, H.-J. Jung, K.-Y. Ryu, M. Nakamura, I.-S. Jang, S.-H. Hong, Y. Lee, H.-J. Lee

This study shows that periodontitis promotes neuroinflammation via bacterial extracellular vesicles that cross the blood-brain barrier and activate TLR4/TLR8 signaling in the brain and trigeminal ganglion.

bioRxiv · Jul 9, 2023Pathology

Palbociclib interferes with replication origin firing in a pRb independent manner

S.-J. Kim, C. Maric, l.-m. Briu, F. Fauchereau, G. Baldacci, M. Debatisse, S. KOUNDRIOUKOFF, J. C. cadoret

This paper shows palbociclib disrupts DNA replication in pRb-deficient cells by reducing origin firing and pre-initiation complex loading, leading to replicative stress and decreased cell viability.

bioRxiv · Sep 21, 2022 · PreprintCancer Biology

Development and Evaluation of RT-LAMP Assays to Identify Variants of SARS-CoV-2

G.-S. Park, S.-J. Kim, J.-S. Maeng

This study develops and evaluates RT-LAMP assays for detecting SARS-CoV-2 variant deletions and single nucleotide substitutions, discussing their limitations in variant surveillance.

bioRxiv · Jun 16, 2022 · PreprintMicrobiology

Ocular tropism of SARS-CoV-2 with retinal inflammation through neuronal invasion in animal models

G. U. Jeong, H.-J. Kwon, H. W. Moon, G. Y. Yoon, H. J. Shin, J. S. Chae, S.-J. Kim, I.-C. Lee, K.-D. Kim, D.-G. Ahn, S. Mahalingam, Y.-C. Kwon

This study investigates SARS-CoV-2 ocular tropism and neuroinvasion in animal models, showing virus spread to the brain and eyes via nerves and causing retinal inflammation.

bioRxiv · Apr 17, 2022 · PreprintMicrobiology

Production of novel biosurfactant by a new yeast species isolated from Prunus mume Sieb. et Zucc.

J.-S. Kim, M. Lee, D.-W. Ki, S.-W. Kwon, Y.-J. Ko, J.-S. Kim, B.-S. Yun, S.-J. Kim

This paper isolates a novel yeast strain JAF-11 capable of producing a new biosurfactant with unique chemical properties and potential industrial applications.

bioRxiv · Mar 15, 2022 · PreprintMicrobiology

Comparison of Plaque Size, Thermal Stability, and Replication Rate among SARS-CoV-2 Variants of Concern

G. U. Jeong, G. Y. Yoon, H. W. Moon, W. Lee, I. Hwang, H. S. Kim, K.-D. Kim, C. Kim, D.-G. Ahn, B.-T. Kim, S.-J. Kim, Y.-C. Kwon

This study compares plaque size, thermal stability, and replication rates of four SARS-CoV-2 variants of concern and finds differences in these characteristics among them.

Viruses · Dec 30, 2021Peer-reviewedMicrobiology

Disruption of Brachypodium Lichenase Alters Metabolism of Mixed-linkage Glucan and Starch

M. Fan, J. K. Jensen, S. Zemelis-Durfee, S.-J. Kim, J.-Y. Chan, C. M. Beaudry, F. Brandizzi, C. G. Wilkerson

This study identifies BdLCH1, a lichenase in Brachypodium, and shows its role in MLG degradation in vegetative tissues and starch breakdown in darkness.

bioRxiv · Aug 20, 2021Plant Biology

Soluble Spike DNA vaccine provides long-term protective immunity against SAR-CoV-2 in mice and nonhuman primates

Y. B. Seo, Y. S. Suh, J. I. Ryu, H. Jang, H. Oh, B.-S. Koo, S.-H. Seo, J. J. Hong, M. Song, S.-J. Kim, Y. C. Sung

This study develops a DNA vaccine against SARS-CoV-2, GX-19, showing protective immunity in mice and nonhuman primates with durable antibody and T cell responses.

bioRxiv · Oct 9, 2020Immunology

Root electrotropism in Arabidopsis does not depend on auxin distribution but requires cytokinin biosynthesis

M. Salvalaio, N. Oliver, D. Tiknaz, M. Schwarze, N. Kral, S.-J. Kim, G. Sena

This study investigates root electrotropism in Arabidopsis, finding it does not rely on auxin distribution but requires cytokinin biosynthesis and follows a power law dose-response kinetics.

bioRxiv · Jul 30, 2020Plant Biology

Although host-related factors are important for the formation of gut microbiota, environmental factors cannot be ignored

Y. Jung, D. Kerfahi, H. Q. Pham, H. Son, J. C. Ibal, M.-K. Park, Y.-J. Park, C. E. Park, S.-D. Choi, Y. Jo, M.-C. Kim, M. J. Kim, G. U. Kang, H. W. Jo, H. Yun, , J.-H. Shin

This study compares host-related factors and environmental factors in shaping gut microbiota using fecal samples from naval trainees and healthy individuals, finding host factors more influential.

bioRxiv · Feb 3, 2020 · PreprintMicrobiology

Live-cell Imaging Analysis of Antimycin-Type Depsipeptides via Bioorthogonal Stimulated Raman Scattering Microscopy

J. A. Seidel, Y. Miao, W. Porterfield, W. Cai, X. Zhu, S.-J. Kim, F. Hu, S. Bhattarai-Kline, W. Min, W. Zhang

This study uses bioorthogonal SRS microscopy to analyze the intracellular distribution of antimycin-type depsipeptides in living cells, showing their enrichment depends on potency, protein targets, and lipophilicity.

bioRxiv · Mar 21, 2019 · PreprintBioengineering

Deep transfer learning-based hologram classification for molecular diagnostics

S.-J. Kim, C. Wang, B. Zhao, H. Im, J. Min, H. J. Choi, J. Tadros, N. R. Choi, C. M. Castro, R. Weissleder, H. Lee, K. Lee

This paper develops a deep transfer learning method to classify LDIH holograms without image reconstruction, enabling low-cost point-of-care diagnostics.

bioRxiv · Oct 12, 2018Bioengineering

Deconvolution Of Subcellular Protrusion Heterogeneity And The Underlying Actin Regulator Dynamics From Live Cell Imaging

C. Wang, H. J. Choi, S.-J. Kim, A. Desai, N. Lee, D. Kim, Y. Bae, K. Lee

This paper introduces HACKS, a machine learning framework to analyze live cell imaging data and uncover subcellular protrusion heterogeneity and actin regulator dynamics.

bioRxiv · Jan 25, 2018Cell Biology

Quantum chemistry reveals the thermodynamic principles of redoxbiochemistry

A. Jinich, A. Flamholz, H. Ren, S.-J. Kim, B. Sanchez-Lengeling, C. A. R. Cotton, E. Noor, A. Aspuru-Guzik, A. Bar-Even

This study uses quantum chemistry to calculate redox potentials of biochemical reactions, revealing thermodynamic trends and explaining the role of NAD/NADP in cellular metabolism.

bioRxiv · Jan 9, 2018Biochemistry

The industrial anaerobe Clostridium acetobutylicum uses polyketides to regulate butanol production and differentiation

N. Herman, S.-J. Kim, J. S. Li, W. Cai, H. Koshino, W. Zhang

This study identifies a novel family of polyketides in Clostridium acetobutylicum that regulate butanol production and differentiation processes.

bioRxiv · May 18, 2017Microbiology