ThX - A next-generation probe for the early detection of amyloid aggregates
L.-M. Needham, J. Weber, J. A. Varela, J. W. B. Fyfe, D. T. Do, C. K. Xu, B. Keenlyside, R. Cliffe, D. Klenerman, C. M. Dobson, C. A. Hunter, S. E. Bohndiek, T. N. Snaddon, S. F. Lee
This paper introduces ThX, a new fluorescent probe for detecting amyloid aggregates, showing improved brightness and binding affinity over ThT.
bioRxiv · Jul 24, 2019Biophysics