Author

J. A. Vargas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Organism:plant (other)· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

J. A. Lemos· 2 shared J. Abranches· 2 shared T. Ganguly· 2 shared A. Aviles-Reyes· 1 shared A. M. Burroughs· 1 shared A. N. Conte· 1 shared A. R. Lopes· 1 shared A. T. Whiteley· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersMicrobiology

J. A. Lemos

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Bacterial NLR-related proteins protect against phage

E. M. Kibby, A. N. Conte, A. M. Burroughs, T. A. Nagy, J. A. Vargas, L. Aravind, A. T. Whiteley

This study identifies bacterial NLR-related proteins that defend against phages, showing they share structural and functional features with eukaryotic NLRs and use a conserved signaling mechanism.

bioRxiv · Jul 19, 2022Microbiology

Structural Characterization of L-Galactose Dehydrogenase: A Key Enzyme for Vitamin C Biosynthesis

J. A. Vargas, D. A. Leonardo, H. D. M. Pereira, A. R. Lopes, H. N. Rodriguez, M. Cobos, J. L. Marapara, J. C. Castro, R. C. Garratt

This paper presents the crystal structure of L-galactose dehydrogenase from spinach, revealing its structural features and substrate specificity, and suggests its role in vitamin C biosynthesis.

bioRxiv · Apr 15, 2022 · PreprintBiophysics

Amyloid aggregation of Streptococcus mutans Cnm influences its collagen-binding activity

N. de Mojana di Cologna, S. Samaddar, C. Valle, J. A. Vargas, A. Aviles-Reyes, J. Morales, T. Ganguly, R. Pileggi, L. J. Brady, J. A. Lemos, J. Abranches

This study shows that Cnm, a collagen-binding protein in S. mutans, forms amyloids that lose collagen-binding activity, modulating biofilm function.

Applied and Environmental Microbiology · Oct 14, 2021Peer-reviewedMicrobiology

Manganese uptake, mediated by SloABC and MntH, is essential for the fitness of Streptococcus mutans

J. A. Lemos, J. K. Kajfasz, T. Ganguly, G. A. Spatafora, J. Abranches, C. Katrak, J. A. Vargas, L. T. Wright, Z. T. Peters

This study shows that manganese uptake via SloABC and MntH is critical for Streptococcus mutans growth and virulence under manganese restriction.

bioRxiv · Oct 24, 2019Microbiology