Author

G. A. Spatafora

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Cowan· 1 shared A. DePaolo· 1 shared A. Glasfeld· 1 shared C. Katrak· 1 shared C. R. Davidowitz· 1 shared F. Seybert· 1 shared H. E. Driscoll· 1 shared I. Y. Drummond· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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1 shared paperMicrobiology

A. Cowan

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4 papers

Recent·Most cited

Small regulatory RNAs are mediators of the Streptococcus mutans SloR regulon

I. Y. Drummond, A. DePaolo, M. Krieger, H. E. Driscoll, K. Eckstrom, G. A. Spatafora

This study identifies small regulatory RNAs (sRNAs) as mediators of the SloR and manganese regulons in Streptococcus mutans, linking sRNA expression to virulence gene control and metal ion homeostasis.

bioRxiv · Jun 2, 2023 · PreprintMicrobiology

Regulatory involvement of the PerR and SloR metalloregulators in the Streptococcus mutans oxidative stress response

T. R. Ruxin, J. A. Schwartzman, C. R. Davidowitz, R. A. Haney, G. A. Spatafora

This study investigates the role of PerR and SloR metalloregulators in S. mutans oxidative stress response, showing their regulatory relationship and impact on antioxidant gene expression.

bioRxiv · Dec 15, 2020Microbiology

Manganese uptake, mediated by SloABC and MntH, is essential for the fitness of Streptococcus mutans

J. A. Lemos, J. K. Kajfasz, T. Ganguly, G. A. Spatafora, J. Abranches, C. Katrak, J. A. Vargas, L. T. Wright, Z. T. Peters

This study shows that manganese uptake via SloABC and MntH is critical for Streptococcus mutans growth and virulence under manganese restriction.

bioRxiv · Oct 24, 2019Microbiology

Autoregulation of the S. mutans SloR metalloregulator is constitutive and driven by an independent promoter

P. Monette, R. Brach, A. Cowan, R. Winters, J. Weisman, F. Seybert, K. Goguen, J. Chen, A. Glasfeld, G. A. Spatafora

This study identifies an independent promoter for SloR in S. mutans, showing SloR autoregulates via transcriptional activation of its own promoter and repression of the sloABC operon.

bioRxiv · Apr 14, 2018Microbiology