Author

J. B. Westover

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:human· 3 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Tapparel· 2 shared A. B. Ward· 1 shared A. Betancour· 1 shared A. C.-A. Zwygart· 1 shared A. R. Arment· 1 shared A. Tiwari· 1 shared A. W. Thurston· 1 shared B. Gowen· 1 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

C. Tapparel

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Development of Broad-spectrum β-cyclodextrins-Based Nanomaterials Against Influenza Viruses

A. C.-A. Zwygart, C. Medaglia, Y. Zhu, E. B. Tarbet, J. B. Westover, C. Fage, D. Le Roy, T. Roger, S. Constant, S. Huang, F. Stellacci, P. J. Silva, C. Tapparel

This study develops CD-SA, a β-cyclodextrin-based nanomaterial that acts as a potent broad-spectrum antiviral against influenza A and B viruses, showing higher efficacy than Oseltamivir in ex vivo and in vivo tests.

bioRxiv · Mar 5, 2024Microbiology

Safety, Immunogenicity and Efficacy of a Recombinant Vesicular Stomatitis Virus Vectored Vaccine Against Severe Fever with Thrombocytopenia Syndrome and Heartland Bandaviruses

P. Hicks, J. B. Westover, T. B. Manzoni, B. Roper, G. L. Rock, K. M. Boardman, D. J. Blotter, B. Gowen, P. Bates

This paper develops a recombinant VSV vaccine against SFTSV and Heartland virus, showing safety, immunogenicity, and cross-protection in mice.

bioRxiv · Nov 29, 2021 · PreprintMicrobiology

Canonical features of human antibodies recognizing the influenza hemagglutinin trimer interface

S. J. Zost, J. Dong, I. M. Gilchuk, P. Gilchuk, N. J. Thornburg, S. Bangaru, N. Kose, J. A. Finn, R. Bombardi, C. Soto, R. S. Nargi, R. P. Irving, N. Suryadevara, J. B. Westover, R. H. Carnahan, , J. E. Crowe

The paper identifies common genetic and structural features of human antibodies recognizing the influenza HA trimer interface, suggesting it as a target for vaccine design.

bioRxiv · Dec 31, 2020Immunology

A Nasal Spray Solution of Grapefruit Seed Extract plus Xylitol Displays Virucidal Activity Against SARS-Cov-2 In Vitro

G. A. Ferrer, A. Betancour, C. C. Go, H. Vazquez, J. B. Westover, V. Cagno, C. Tapparel, M. A. Sanchez-Gonzalez

This paper tests a nasal spray containing xylitol and grapefruit seed extract for in vitro virucidal activity against SARS-CoV-2, finding it reduces infectious virus by over 3 log10.

bioRxiv · Nov 23, 2020 · PreprintCell Biology

PT150 is a modulator of glucocorticoid and androgen receptors with antiviral activity against SARS-CoV-2.

N. D. Theise, A. R. Arment, D. Chakravarty, J. M. H. Gregg, I. M. Jacobson, K. H. Jung, S. S. Nair, A. Tiwari, A. W. Thurston, J. Van Drie, J. B. Westover

PT150 inhibits SARS-CoV-2 with EC90 5.55 M in human bronchial epithelial cells by downregulating AR and modulating ACE2 and TMPRSS2.

bioRxiv · Jul 12, 2020Microbiology