Author

C. Tapparel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 5 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 1

Frequent Co-Authors

V. Cagno· 5 shared C. Medaglia· 4 shared F. Stellacci· 3 shared A. C.-A. Zwygart· 2 shared G. Mathez· 2 shared J. B. Westover· 2 shared L. Kaiser· 2 shared S. Constant· 2 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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5 shared papersMicrobiology

V. Cagno

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Development of Broad-spectrum β-cyclodextrins-Based Nanomaterials Against Influenza Viruses

A. C.-A. Zwygart, C. Medaglia, Y. Zhu, E. B. Tarbet, J. B. Westover, C. Fage, D. Le Roy, T. Roger, S. Constant, S. Huang, F. Stellacci, P. J. Silva, C. Tapparel

This study develops CD-SA, a β-cyclodextrin-based nanomaterial that acts as a potent broad-spectrum antiviral against influenza A and B viruses, showing higher efficacy than Oseltamivir in ex vivo and in vivo tests.

bioRxiv · Mar 5, 2024Microbiology

Enterovirus A71 adaptation to heparan sulfate comes with capsid stability tradeoff

H. K. Tee, G. Mathez, V. Cagno, A. Antanasijevic, S. Clement, C. Tapparel

This study shows that EV-A71 adapts to heparan sulfate by losing pH-dependent uncoating, which compromises capsid stability and affects viral fitness in vivo.

bioRxiv · Feb 23, 2024Microbiology

Trapping virus-loaded aerosols using granular protein nanofibrils and iron oxyhydroxides nanoparticles

A. Armanious, H. Wang, P. Alpert, C. Medaglia, M. Peydayesh, A. C.-A. Zwygart, C. Gübeli, S. Handschin, S. Bolisetty, M. Ammann, C. Tapparel, F. Stellacci, R. Mezzenga

This paper introduces an environmentally-friendly aerosol filter made from whey protein nanofibrils and iron oxyhydroxides nanoparticles that efficiently traps various viruses.

bioRxiv · Jun 29, 2022Microbiology

Geneticin shows selective antiviral activity against SARS-CoV-2 by interfering with programmed -1 ribosomal frameshifting

C. Varricchio, G. Mathez, T. Pillonel, C. Bertelli, L. Kaiser, C. Tapparel, A. Brancale, V. Cagno

This study shows geneticin inhibits SARS-CoV-2 by reducing -1 ribosomal frameshifting, effective against multiple variants in cell lines and tissue models.

bioRxiv · Mar 8, 2022Microbiology

A Nasal Spray Solution of Grapefruit Seed Extract plus Xylitol Displays Virucidal Activity Against SARS-Cov-2 In Vitro

G. A. Ferrer, A. Betancour, C. C. Go, H. Vazquez, J. B. Westover, V. Cagno, C. Tapparel, M. A. Sanchez-Gonzalez

This paper tests a nasal spray containing xylitol and grapefruit seed extract for in vitro virucidal activity against SARS-CoV-2, finding it reduces infectious virus by over 3 log10.

bioRxiv · Nov 23, 2020 · PreprintCell Biology

Methylene Blue has a potent antiviral activity against SARS-CoV-2 in the absence of UV-activation in vitro

V. Cagno, C. Medaglia, A. Cerny, T. Cerny, C. Tapparel, E. Cerny

This study demonstrates that methylene blue inactivates SARS-CoV-2 at low micromolar concentrations without UV activation in vitro.

bioRxiv · Aug 14, 2020Microbiology

Non-Toxic Virucidal Macromolecules Show High Efficacy Against Influenza Virus Ex Vivo and In Vivo

O. Kocabiyik, V. Cagno, P. Jacob Silva, Y. Zhu, L. Sedano, Y. Bhide, J. Mettier, C. Medaglia, B. Da Costa, S. Constant, S. Huang, L. Kaiser, W. Hinrichs, A. Huckriede, R. Le Goffic, , F. Stellacci

The paper develops non-toxic virucidal macromolecules effective against multiple influenza strains in vitro and in vivo.

bioRxiv · Mar 18, 2020Microbiology