Author

J. Baran-Gale

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

F. Dhalla· 2 shared S. Maio· 2 shared A. E. Handel· 1 shared A. Maynard· 1 shared A. Nakamura· 1 shared A. P. May· 1 shared C. Flowers· 1 shared C. L. Kurtz· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

F. Dhalla

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

miR-29 is an important driver of aging-related phenotypes

V. Swahari, A. Nakamura, E. Hollville, Y.-H. Hung, M. Kanke, C. L. Kurtz, X. M. Caravia, S. He, J. Krishnamurthy, S. Kapoor, V. Prasad, C. Flowers, M. Beck, J. Baran-Gale, N. Sharpless, , M. Deshmukh

This study identifies miR-29 as a key driver of aging-related phenotypes by showing its upregulation in aging models and its ability to induce aging traits when overexpressed.

bioRxiv · Nov 29, 2022Physiology

Ageing compromises mouse thymus function and remodels epithelial cell differentiation

C. P. Ponting, J. Baran-Gale, M. D. Morgan, S. Maio, F. Dhalla, I. Calvo-Asensio, M. Deadman, A. E. Handel, A. Maynard, S. Chen, F. Green, R. Sit, N. Neff, S. Darmanis, W. Tan, , G. A. Holländer

This study investigates how ageing affects mouse thymus function, revealing that progenitor cell differentiation is disrupted, leading to impaired T cell selection and self-antigen representation.

bioRxiv · Mar 2, 2020Immunology

Biologically indeterminate yet ordered promiscuous gene expression in single medullary thymic epithelial cells

F. Dhalla, J. Baran-Gale, S. Maio, L. Chappell, G. A. Hollander, C. Ponting

The paper analyzes single mTEC transcriptomes to determine if promiscuous gene expression is stochastic or coordinated, finding it is ordered yet biologically indeterminate.

bioRxiv · Feb 19, 2019Immunology