Author

J. Blum

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Goginashvili· 1 shared A. Herrera· 1 shared A. Rashidfarrokhi· 1 shared A. Tsirigos· 1 shared B. Karadal-Ferrena· 1 shared C. Bahamon· 1 shared C. Liu· 1 shared C. M. Rudin· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

A. Goginashvili

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2 papers

Recent·Most cited

Glutamine antagonist DRP-104 suppresses tumor growth and enhances response to checkpoint blockade in KEAP1 mutant lung cancer

R. Pillai, S. E. LeBoeuf, Y. Hao, C. New, J. Blum, A. Rashidfarrokhi, S. M. Huang, C. Bahamon, W. L. Wu, B. Karadal-Ferrena, A. Herrera, E. Ivanova, M. Cross, J. P. Bossowski, H. Ding, , T. Papagiannakopoulos

This study shows that DRP-104, a glutamine antagonist, suppresses KEAP1 mutant lung tumor growth and enhances response to checkpoint blockade by inhibiting glutamine metabolism and improving T cell function.

bioRxiv · Jun 27, 2023 · PreprintCancer Biology

Heat shock chaperone HSPB1 regulates cytoplasmic TDP-43 phase separation and liquid-to-gel transition

S. Lu, J. Hu, O. A. Arogundade, A. Goginashvili, S. Vazquez-Sanchez, J. K. Diedrich, J. Gu, J. Blum, S. Oung, H. Yu, J. Ravits, C. Liu, J. R. Yates, D. W. Cleveland

This study shows HSPB1 regulates cytoplasmic TDP-43 phase separation and liquid-to-gel transition, with implications for neurodegenerative diseases like ALS.

bioRxiv · Oct 14, 2021Cell Biology