Author

J. Brennecke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

D. Handler· 2 shared A. Chavan· 1 shared A. Sintsova· 1 shared A. Yeroslaviz· 1 shared B. Hampoelz· 1 shared B. Rafanel· 1 shared C. Kosiol· 1 shared C. Schloetterer· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersEvolutionary Biology

D. Handler

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

In-cell structure and snapshots of copia retrotransposons in intact tissue by cryo-electron tomography

S. Klumpe, K. A. Senti, F. Beck, J. Sachweh, B. Hampoelz, P. Ronchi, A. Yeroslaviz, J. Briggs, J. Brennecke, M. Beck, J. M. Plitzko

This study uses cryo-ET to visualize copia retrotransposon structure in Drosophila cells, revealing nuclear clustering and size selection during gametogenesis.

Cell · Apr 1, 2025Peer-reviewedBiophysics

Functional Adaptations of Endogenous Retroviruses to the Drosophila Host Underlie their Evolutionary Diversification

K.-A. Senti, D. Handler, B. Rafanel, C. Kosiol, C. Schloetterer, J. Brennecke

The paper investigates how endogenous retroviruses in Drosophila have evolved to adapt their expression patterns and infectivity, leading to niche-specific diversification.

bioRxiv · Aug 3, 2023 · PreprintEvolutionary Biology

Multi-tissue proteomics identifies a link between satellite DNA organization and heritable transposon repression in Drosophila

A. Chavan, L. Skrutl, F. Uliana, M. Pfister, F. Braendle, L. Tirian, D. Baptista, D. Handler, D. F. Burke, A. Sintsova, P. Beltrao, J. Brennecke, M. Jagannathan

bioRxiv · Jul 11, 2023 · PreprintCell Biology