Deterministic scRNA-seq of individual intestinal organoids reveals new subtypes and coexisting distinct stem cell pools
J. Bues, M. Biocanin, J. Pezoldt, R. Dainese, A. Chrisnandy, S. Rezakhani, W. Saelens, V. Gardeux, R. Gupta, J. Russeil, Y. Saeys, E. Amstad, M. Claassen, M. Lutolf, B. Deplancke
The paper introduces DisCo, a deterministic scRNA-seq method for small tissue samples, revealing new intestinal organoid subtypes and stem cell populations.
bioRxiv · May 19, 2020 · PreprintBioengineering