Author

W. Saelens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Assay:scRNA-seq· 5 Organism:mouse· 4 Approach:experimental assay· 3 Approach:statistical model· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Organism:human· 2

Frequent Co-Authors

B. Deplancke· 4 shared J. Russeil· 3 shared V. Gardeux· 3 shared Y. Saeys· 3 shared G. van Mierlo· 2 shared J. Pezoldt· 2 shared M. Biocanin· 2 shared P. Rainer· 2 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersCell Biology

B. Deplancke

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Author profile →

5 papers

Recent·Most cited

Dissecting reprogramming heterogeneity at single-cell resolution using scTF-seq

W. Liu, W. Saelens, P. Rainer, M. Biocanin, V. Gardeux, A. Gralak, G. van Mierlo, J. Russeil, T. Liu, W. Chen, B. Deplancke

The paper introduces scTF-seq, a method to study TF dose-dependent reprogramming in mouse MSCs, revealing heterogeneity in cell fate and TF sensitivity.

bioRxiv · Jan 30, 2024Cell Biology

A human omentum-specific mesothelial-like stromal population inhibits adipogenesis through IGFBP2 secretion

R. Ferrero, P. Rainer, J. Russeil, M. Zachara, J. Pezoldt, G. van Mierlo, V. Gardeux, W. Saelens, D. Alpern, L. Favre, S. Mantziari, T. Zingg, N. Pitteloud, M. Suter, M. Matter, , B. Deplancke

The paper identifies an omental-specific stromal population that inhibits adipogenesis via IGFBP2 secretion in human adipose tissue.

bioRxiv · May 1, 2023Cell Biology

CD8 memory precursor cells generation is a continuous process

H. Todorov, M. Prieux, D. Laubreton, M. Bouvier, S. Wang, S. De Bernard, C. Arpin, R. Cannoodt, W. Saelens, A. Bonnaffoux, O. Gandrillon, F. Crauste, Y. Saeys, J. Marvel

The paper identifies that memory precursor cells are continuously generated over time following acute infection, with increased numbers and effector gene expression observed later.

bioRxiv · Feb 9, 2022Immunology

Spatial proteogenomics reveals distinct and evolutionarily-conserved hepatic macrophage niches

M. Guilliams, J. Bonnardel, B. Haest, B. Vanderborght, A. Bujko, L. Martens, T. Thone, R. Browaeys, F. F. De Ponti, A. Remmerie, C. Wagner, B. Vanneste, C. Zwicker, T. Vanhalewyn, A. Goncalves, , C. L. Scott

This study creates a spatial proteogenomic atlas of the liver across species, identifying conserved macrophage niches and their regulatory mechanisms.

bioRxiv · Oct 15, 2021Immunology

Deterministic scRNA-seq of individual intestinal organoids reveals new subtypes and coexisting distinct stem cell pools

J. Bues, M. Biocanin, J. Pezoldt, R. Dainese, A. Chrisnandy, S. Rezakhani, W. Saelens, V. Gardeux, R. Gupta, J. Russeil, Y. Saeys, E. Amstad, M. Claassen, M. Lutolf, B. Deplancke

The paper introduces DisCo, a deterministic scRNA-seq method for small tissue samples, revealing new intestinal organoid subtypes and stem cell populations.

bioRxiv · May 19, 2020 · PreprintBioengineering