Author

M. Claassen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:deep learning· 3 Approach:statistical model· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

R. Gupta· 2 shared A. Chrisnandy· 1 shared A. Oxenius· 1 shared B. Deplancke· 1 shared B. Walter· 1 shared C. Gordijn· 1 shared C. K. Woods· 1 shared C. Roggia· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersImmunology

R. Gupta

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

An assessment of Nano-RECall: Interpretation of Oxford Nanopore sequence data for HIV-1 drug resistance testing

K. E. Delaney, T. Ngobeni, C. K. Woods, C. Gordijn, M. Claassen, U. Parikh, P. R. Harrigan, G. U. Van Zyl

This paper evaluates the Nano-RECall pipeline for interpreting HIV-1 drug resistance from Oxford Nanopore sequencing data, finding it provides Sanger-equivalent results with low read coverage.

bioRxiv · Jul 22, 2022 · PreprintMicrobiology

Privacy-Preserving Federated Neural Network Learning for Disease-Associated Cell Classification

S. Sav, J.-P. Bossuat, J. R. Troncoso-Pastoriza, M. Claassen, J.-P. Hubaux

This paper develops a privacy-preserving federated learning framework for disease-associated cell classification, achieving comparable accuracy to centralized methods with faster execution.

bioRxiv · Jan 10, 2022Cell Biology

Fate trajectories of CD8+ T cells in chronic LCMV infection

D. Cerletti, I. Sandu, R. Gupta, A. Oxenius, M. Claassen

This study uses scRNA-seq to analyze CD8+ T cell fate trajectories during chronic LCMV infection, identifying a branching point where cells commit to exhausted or memory-like lineages.

bioRxiv · Dec 22, 2020 · PreprintImmunology

Genome-wide CRISPR and small-molecule screens uncover targetable dependencies in ATRT

D. J. Merk, S. Hirsch, F. Tsiami, B. Walter, L. A. Haeusser, S. Babaei, J. Admar, N. Casadei, C. Roggia, M. Spohn, J. Schittenhelm, S. Singer, U. Schueller, F. Piccioni, N. S. Persky, , G. Tabatabai

This study identifies targetable genetic dependencies in ATRT using CRISPR and small-molecule screens, revealing CDK4/6 inhibitors as potent therapeutic options.

bioRxiv · Dec 9, 2020 · PreprintCancer Biology

Deterministic scRNA-seq of individual intestinal organoids reveals new subtypes and coexisting distinct stem cell pools

J. Bues, M. Biocanin, J. Pezoldt, R. Dainese, A. Chrisnandy, S. Rezakhani, W. Saelens, V. Gardeux, R. Gupta, J. Russeil, Y. Saeys, E. Amstad, M. Claassen, M. Lutolf, B. Deplancke

The paper introduces DisCo, a deterministic scRNA-seq method for small tissue samples, revealing new intestinal organoid subtypes and stem cell populations.

bioRxiv · May 19, 2020 · PreprintBioengineering