Author

J. C. Boyington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

J. R. Mascola· 4 shared Y. Tsybovsky· 4 shared J. Gorman· 3 shared P. D. Kwong· 3 shared T. Stephens· 3 shared T. Zhou· 3 shared A. B. McDermott· 2 shared A. Cagigi· 2 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersImmunology

J. R. Mascola

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Prefusion-Stabilized Lassa Virus Trimer Identifies Neutralizing Nanobodies and Reveals an Apex-Situated Site of Vulnerability

J. Gorman, C. S.-F. Cheung, Z. Duan, Y. Sun, P. Wang, J. C. Boyington, A. Biju, T. Bylund, C. Cheng, L. Ou, T. Stephens, Y. Tsybovsky, R. Verardi, S. Wang, Y. Yang, , P. D. Kwong

This paper develops a prefusion-stabilized Lassa virus GPC, identifies a neutralizing nanobody, and reveals a cleavage-dependent site of vulnerability at the trimer apex.

bioRxiv · Apr 21, 2022 · PreprintImmunology

Vaccine-elicitation of cross-group neutralizing protective antibodies to influenza A viruses

S. M. Moin, J. C. Boyington, S. Boyoglu-Barnum, R. A. Gillespie, G. Cerutti, C. S.-F. Cheung, A. Cagigi, J. R. Gallagher, J. Brand, M. Prabhakaran, Y. Tsybovsky, T. Stephens, B. E. Fisher, A. Creanga, S. Ataca, , M. Kanekiyo

This study shows that co-immunization with stem immunogens from group 1 and 2 influenza A HAs elicits cross-group neutralizing antibodies and protective immunity in multiple animal models.

bioRxiv · Feb 11, 2022 · PreprintImmunology

Cryo-EM Structures Delineate a pH-Dependent Switch that Mediates Endosomal Positioning of SARS-CoV-2 Spike Receptor-Binding Domains

T. Zhou, Y. Tsybovsky, A. S. Olia, J. Gorman, M. A. Rapp, G. Cerutti, G.-Y. Chuang, P. S. Katsamba, A. Nazzari, J. M. Sampson, A. Schon, P. D. Wang, J. Bimela, W. Shi, I.-T. Teng, , P. D. Kwong

This paper uses cryo-EM to show how SARS-CoV-2 spike protein undergoes pH-dependent structural changes that affect ACE2 binding and antibody evasion.

bioRxiv · Jul 4, 2020 · PreprintImmunology

Design of nanoparticulate group 2 influenza hemagglutinin stem antigens that activate unmutated ancestor B cell receptors of broadly neutralizing antibody lineages

K. S. Corbett, S. M. Moin, H. M. Yassine, A. Cagigi, M. Kanekiyo, S. Boyoglu-Barnum, S. I. Myers, Y. Tsybovsky, A. K. Wheatley, C. A. Schramm, R. A. Gillespie, W. Shi, L. Wang, Y. Zhang, S. F. Andrews, , J. C. Boyington

This study designs nanoparticle-based influenza HA stem antigens that activate unmutated B cell receptors of broadly neutralizing antibodies, potentially enabling cross-group immunity.

bioRxiv · Dec 17, 2018Immunology