Author

J. Cruz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biophysics· 1 Ecology· 1 Evolutionary Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 4 Organism:human· 4 Research Focus:host-pathogen & immune response· 3 Assay:imaging· 3 Approach:deep learning· 2 Assay:DNA methylation· 2 Research Focus:drug response / drug discovery· 2

Frequent Co-Authors

C. Johnson· 2 shared J. Mei· 2 shared K. Saini· 2 shared M. Masaeli· 2 shared N. Li· 2 shared R. W. Finberg· 2 shared A. B. Lima· 1 shared A. Becerra-Artiles· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersPathology

C. Johnson

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Author profile →

9 papers

Recent·Most cited

Spatial behaviors and seasonal habitat use of the increasingly endangered thick-billed parrot (Rhynchopsitta pachyrhyncha)

J. K. Sheppard, J. Cruz, L. F. T. Gonzalez, M. A. C. Nieto, R. R. Swaisgood, N. Lamberski

This study tracks thick-billed parrots to reveal their seasonal migration patterns, overwintering sites, and habitat preferences, highlighting conservation needs for their survival.

Global Ecology and Conservation · Dec 1, 2023Peer-reviewedEcology

Artificial intelligence-driven morphology-based enrichment of malignant cells from body fluid

A. Mavropoulos, C. Johnson, V. Lu, J. Nieto, E. Schneider, K. Saini, M. L. Phelan, L. Hsie, M. Wang, J. Cruz, J. Mei, J. Kim, Z. Lian, N. Li, S. C. Boutet, , J. Rao

This study uses deep learning and microfluidic sorting to enrich malignant cells from body fluids, improving detection of tumor fractions and mutations.

bioRxiv · Jan 24, 2023Pathology

Buforin II-Escherichia coli's DNA interactome: Detailed biophysical characterization revealed nanoscale complexes likely formed by DNA supercoiling

D. Rubio-Olaya, J. Cifuentes, P. Ruiz-Puentes, O. A. Castaneda, L. H. Reyes, J. Duitama, C. Munoz, J. Cruz

This study characterizes the interaction between BUFII and E. coli DNA using biophysical methods, revealing nanoscale complexes formed through electrostatic interactions and suggesting DNA supercoiling as a potential mechanism.

bioRxiv · May 20, 2022 · PreprintBiophysics

Realtime morphological characterization and sorting of unlabeled viable cells using deep learning

M. Salek, N. Li, H.-P. Chou, K. Saini, A. Jovic, K. B. Jacobs, C. Johnson, E. J. Lee, C. Chang, P. Nguyen, J. Mei, K. P. Pant, A. Y. Wong-Thai, Q. F. Smith, S. Huang, , M. Masaeli

COSMOS enables real-time, unlabeled cell sorting based on morphology using deep learning, achieving high enrichment of viable cells for functional analysis.

bioRxiv · Feb 28, 2022 · PreprintCell Biology

Broadly-recognized, cross-reactive SARS-CoV-2 CD4 T cell epitopes are highly conserved across human coronaviruses and presented by common HLA alleles

A. Becerra-Artiles, J. M. Calvo-Calle, M. Co, P. Nanaware, J. Cruz, G. C. Weaver, L. Lu, C. Forcini, R. W. Finberg, A. Moormann, L. J. Stern

The paper identifies a conserved SARS-CoV-2 CD4 T cell epitope recognized by diverse T cells across populations and HLA alleles.

bioRxiv · Jan 20, 2022Immunology

Cell culture model system utilizing engineered A549 cells to express high levels of ACE2 and TMPRSS2 for investigating SARS-CoV-2 infection and antivirals

C.-W. Chang, K. M. Parsi, M. Somasundaran, E. Vanderleeden, J. Cruz, A. Cousineau, P. Liu, Q. Li, Y. Wang, R. Maehr, J. P. Wang, R. W. Finberg

This paper develops an engineered A549 cell model overexpressing ACE2 and TMPRSS2 to study SARS-CoV-2 infection and antiviral responses.

bioRxiv · Dec 31, 2021Cell Biology

Expression and novel alternative purification of the recombinant nucleocapsid (N) protein of SARS-CoV-2 in Escherichia coli for the serodiagnosis of COVID-19

J. D. Rosales, W. Quintero, J. Cruz, B. Perdomo, M. Quintero, M. Bastidas, J. D. Lugo, K. R. Rodriguez, J. C. Freites-Perez, A. Castillo

This paper describes a method to express and purify the SARS-CoV-2 nucleocapsid protein in E. coli for use in serological COVID-19 diagnostics.

bioRxiv · Nov 10, 2021 · PreprintCell Biology

Recombinant haplotypes reflect sexual reproduction in symbiotic arbuscular mycorrhizal fungi

I. D. Mateus, B. Auxier, M. M. S. Ndiaye, J. Cruz, S.-J. Lee, I. R. Sanders

The paper uses genome sequences to show that dikaryon AMF genomes exhibit reciprocal recombination, supporting a sexual rather than parasexual life cycle.

bioRxiv · Mar 5, 2021 · PreprintEvolutionary Biology

DETECTION AND MOLECULAR EPIDEMIOLOGY OF HUMAN BOCAVIRUS IN CHILDREN WITH ACUTE GASTROENTERITIS FROM BRAZIL

L. Soares, A. B. Lima, K. Pantoja, P. Lobo, J. Cruz, D. Bezerra, R. Bandeira, S. Guerra, J. Mascarenhas

This study detects HBoV in Brazilian children with acute gastroenteritis and identifies its prevalence and co-infections with rotavirus A.

bioRxiv · Aug 30, 2018Microbiology