Author

J. D. Edgeworth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Assay:proteomics· 2 Organism:human· 1

Frequent Co-Authors

A. Kurshan· 2 shared J. Zhou· 2 shared K. J. Doores· 2 shared K. Sukhova· 2 shared L. B. Snell· 2 shared T. P. Peacock· 2 shared W. S. Barclay· 2 shared A. Mechaly· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

A. Kurshan

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Author profile →

3 papers

Recent·Most cited

Distinct antigenic properties of the SARS-CoV-2 Omicron lineages BA.4 and BA.5

B. J. Willett, A. Kurshan, N. Thakur, J. Newman, M. Manali, G. Tyson, N. Logan, P. R. Murcia, L. B. Snell, J. D. Edgeworth, J. Zhou, K. Sukhova, G. Amirthalingam, K. Brown, B. Charleston, , T. P. Peacock

This study compares the antigenic properties of SARS-CoV-2 Omicron variants BA.4 and BA.5 with BA.1, BA.2, and vaccine-induced antibodies, finding they are antigenically distinct and show enhanced neutralisation breadth after breakthrough infection.

bioRxiv · May 25, 2022 · PreprintMicrobiology

Omicron breakthrough infections in vaccinated or previously infected hamsters

J. Zhou, K. Sukhova, P. F. McKay, A. Kurshan, Y. Yau, T. Lechmere, J. C. Brown, M. Moshe, R. Kugathasan, L. B. Snell, J. D. Edgeworth, R. J. Shattock, K. J. Doores, T. P. Peacock, W. S. Barclay

This study shows Delta and Omicron SARS-CoV-2 variants do not provide cross-protective immunity against reinfection in hamsters.

bioRxiv · May 20, 2022Microbiology

Therapeutic antibodies, targeting the SARS-CoV-2 spike N-terminal domain, protect lethally infected K18-hACE2 mice

T. Noy-Porat, A. Mechaly, Y. Levy, E. Makdasi, R. Alcalay, D. Gur, M. Aftalion, R. Falach, S. Leviatan Ben-Arye, S. Lazar, A. Zauberman, E. Epstein, T. Chitlaru, S. Weiss, H. Achdout, , R. Rosenfeld

This study identifies and characterizes neutralizing antibodies targeting the SARS-CoV-2 spike N-terminal domain, showing their protective efficacy in mice.

bioRxiv · Feb 2, 2021Immunology