Author

K. Sukhova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 4 Approach:experimental assay· 3 Organism:human· 3 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

T. P. Peacock· 4 shared W. S. Barclay· 4 shared J. C. Brown· 3 shared J. Zhou· 3 shared A. Kurshan· 2 shared A. W. C. Yan· 2 shared D. Bailey· 2 shared J. D. Edgeworth· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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4 shared papersMicrobiology

T. P. Peacock

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Author profile →

4 papers

Recent·Most cited

Modelling the viral dynamics of the SARS-CoV-2 Delta and Omicron variants in different cell types

C. P. McCormack, A. W. C. Yan, J. C. Brown, K. Sukhova, T. P. Peacock, W. S. Barclay, I. Dorigatti

This study models SARS-CoV-2 Delta and Omicron replication in nasal and lung cells, finding Omicron has higher infectivity but lower production rate than Delta, leading to higher transmission in nasal cells and higher severity in lung cells.

bioRxiv · Mar 15, 2023 · PreprintMicrobiology

Distinct antigenic properties of the SARS-CoV-2 Omicron lineages BA.4 and BA.5

B. J. Willett, A. Kurshan, N. Thakur, J. Newman, M. Manali, G. Tyson, N. Logan, P. R. Murcia, L. B. Snell, J. D. Edgeworth, J. Zhou, K. Sukhova, G. Amirthalingam, K. Brown, B. Charleston, , T. P. Peacock

This study compares the antigenic properties of SARS-CoV-2 Omicron variants BA.4 and BA.5 with BA.1, BA.2, and vaccine-induced antibodies, finding they are antigenically distinct and show enhanced neutralisation breadth after breakthrough infection.

bioRxiv · May 25, 2022 · PreprintMicrobiology

Omicron breakthrough infections in vaccinated or previously infected hamsters

J. Zhou, K. Sukhova, P. F. McKay, A. Kurshan, Y. Yau, T. Lechmere, J. C. Brown, M. Moshe, R. Kugathasan, L. B. Snell, J. D. Edgeworth, R. J. Shattock, K. J. Doores, T. P. Peacock, W. S. Barclay

This study shows Delta and Omicron SARS-CoV-2 variants do not provide cross-protective immunity against reinfection in hamsters.

bioRxiv · May 20, 2022Microbiology

The altered entry pathway and antigenic distance of the SARS-CoV-2 Omicron variant map to separate domains of spike protein

T. P. Peacock, J. C. Brown, J. Zhou, N. Thakur, K. Sukhova, J. Newman, R. Kugathasan, A. W. C. Yan, W. Furnon, G. De Lorenzo, V. M. Cowton, D. Reuss, M. Moshe, O. K. Platt, J. L. Quantrill, , W. S. Barclay

This study identifies distinct genetic determinants in the Omicron spike protein for altered cell entry and antigenic properties, showing they are separable and may affect future variant severity and vaccine efficacy.

bioRxiv · Dec 31, 2021 · PreprintMicrobiology