Author

B. J. Willett

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Microbiology· 3 Ecology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Research Focus:host-pathogen & immune response· 5 Assay:proteomics· 4 Organism:human· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

E. C. Thomson· 3 shared N. Logan· 3 shared P. R. Murcia· 3 shared A. M. Szemiel· 2 shared D. Bailey· 2 shared D. G. Streicker· 2 shared E. S. Swai· 2 shared G. Amirthalingam· 2 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

E. C. Thomson

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Global variation in prior exposure shapes antibody neutralization profiles of SARS-CoV-2 variants up to BA.2.86

S. Turner, G. Amirthalingam, D. Bailey, D. H. Barouch, K. R. Bewley, K. Brown, Y. R. Cao, Y.-W. Chan, S. Charlton, DOVE consortium, N. S. Coombes, B. Hallis, D. D. Ho, F. Jian, N. Lasrado, , D. J. Smith

The paper analyzes antibody neutralization data from multiple countries to assess how prior exposure to SARS-CoV-2 variants affects neutralization profiles of BA.2.86 and its descendants.

bioRxiv · Mar 27, 2024 · PreprintImmunology

Rising SARS-CoV-2 Seroprevalence and Patterns of Cross-Variant Antibody Neutralization in UK Domestic Cats

G. B. Tyson, S. Jones, N. Logan, M. McDonald, P. R. Murcia, B. J. Willett, W. Weir, M. J. Hosie

The paper examines SARS-CoV-2 seroprevalence and cross-variant antibody neutralization in UK domestic cats, finding a 3.2% overall seroprevalence with variant-specific responses correlating with human circulation patterns.

bioRxiv · Nov 18, 2022 · PreprintImmunology

Distinct antigenic properties of the SARS-CoV-2 Omicron lineages BA.4 and BA.5

B. J. Willett, A. Kurshan, N. Thakur, J. Newman, M. Manali, G. Tyson, N. Logan, P. R. Murcia, L. B. Snell, J. D. Edgeworth, J. Zhou, K. Sukhova, G. Amirthalingam, K. Brown, B. Charleston, , T. P. Peacock

This study compares the antigenic properties of SARS-CoV-2 Omicron variants BA.4 and BA.5 with BA.1, BA.2, and vaccine-induced antibodies, finding they are antigenically distinct and show enhanced neutralisation breadth after breakthrough infection.

bioRxiv · May 25, 2022 · PreprintMicrobiology

An outbreak of Rift Valley fever among peri-urban dairy cattle in northern Tanzania, 2018

W. A. de Glanville, K. J. Allan, J. M. Nyarobi, K. M. Thomas, F. Lankester, T. Kibona, J. R. Claxton, B. Brennan, R. W. Carter, J. A. Crump, J. E. B. Halliday, G. Ladbury, B. T. Mmbaga, F. Mramba, O. M. Nyasebwa, , S. Cleaveland

The paper reports a previously unreported RVF outbreak in peri-urban dairy cattle in northern Tanzania, identifying 14 abortions and viral shedding in milk.

bioRxiv · Sep 15, 2021 · PreprintEcology

Development of highly potent neutralising nanobodies against multiple SARS-CoV-2 variants including the variant of concern B.1.351

A. M. Sziemel, S.-H. Hwa, A. Sigal, G. Tyson, N. Logan, B. J. Willett, P. J. Durcan

This paper develops potent neutralizing nanobodies against SARS-CoV-2 variants, including B.1.351, to address reduced vaccine efficacy.

bioRxiv · Apr 11, 2021 · PreprintImmunology

In vitro evolution of Remdesivir resistance reveals genome plasticity of SARS-CoV-2

A. M. Szemiel, A. Merits, R. J. Orton, O. MacLean, A. Wickenhagen, G. Lieber, R. M. Pinto, M. L. Turnbull, S. Wang, D. Mair, A. da Silva Filipe, B. J. Willett, S. J. Wilson, A. H. Patel, E. C. Thomson, , M. E. Stewart

This study shows that in vitro evolution of SARS-CoV-2 under remdesivir selects for resistant mutations, but these mutations do not spread widely in global variants.

bioRxiv · Feb 1, 2021Microbiology

Respiratory disease in cats associated with human-to-cat transmission of SARS-CoV-2 in the UK

M. J. Hosie, I. Epifano, V. Herder, R. Orton, A. Stevenson, N. Johnson, E. MacDonald, D. Dunbar, M. McDonald, F. Howie, B. Tennant, D. Herrity, A. C. Filipe, D. G. Streicker, B. J. Willett, , COVID-19 Genomics UK Consortium

This study reports two cases of SARS-CoV-2 infection in UK cats linked to human-to-cat transmission, showing mild to severe respiratory disease and genetic variation in the viral genome.

bioRxiv · Sep 23, 2020 · PreprintMicrobiology

Predicting the presence and titer of rabies virus neutralizing antibodies from low-volume serum samples in low-containment facilities

D. K. Meza, A. Broos, D. J. Becker, A. Behdenna, B. J. Willett, M. Viana, D. G. Streicker

The paper develops a rapid, low-volume rabies virus neutralizing antibody test for low-containment labs, showing moderate sensitivity and high specificity.

bioRxiv · Apr 24, 2020Immunology

Identifying age cohorts responsible for Peste des petits ruminants virus transmission among sheep, goats, and cattle in northern Tanzania

C. M. Herzog, W. A. de Glanville, B. J. Willett, I. M. Cattadori, V. Kapur, P. J. Hudson, J. Buza, E. S. Swai, S. Cleaveland, O. N. Bjornstad

This study estimates age-specific force of infection for Peste des petits ruminants virus in Tanzanian livestock using seroprevalence data, finding weak age heterogeneity and suggesting management systems, not age, should guide control efforts.

bioRxiv · Dec 19, 2019Ecology