A Carbon Nanotube Optical Reporter Maps Endolysosomal Lipid Flux
P. V. Jena, D. Roxbury, T. V. Galassi, L. Akkari, C. P. Horoszko, D. B. Iaea, J. Budhathoki-Uprety, N. H. Pipalia, A. S. Haka, J. D. Harvey, J. Mittal, F. R. Maxfield, J. A. Joyce, D. A. Heller
This paper develops an optical reporter using carbon nanotubes to measure endolysosomal lipid flux in live cells, revealing lipid accumulation in disease models and sub-cellular heterogeneity.
bioRxiv · Aug 28, 2017Bioengineering