Author

J. A. Joyce

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. D. Swett· 1 shared A. Dariush· 1 shared A. Hannuna· 1 shared A. Küpkü Yoldas· 1 shared A. S. Haka· 1 shared A. Salamero-Boix· 1 shared A. Schaeffer· 1 shared B. Bodenmiller· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

A. D. Swett

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Breast Cancer Macrophage Heterogeneity and Self-renewal are Determined by Spatial Localization

N. Ben-Chetrit, X. Niu, J. Sotelo, A. D. Swett, V. K. Rajasekhar, M. S. Jiao, C. M. Stewart, P. Bhardwaj, S. Kottapalli, S. Ganesan, P.-L. Loyher, C. Potenski, A. Hannuna, K. A. Brown, N. M. Iyengar, , D. A. Landau

This study identifies spatial localization as a key determinant of macrophage heterogeneity and self-renewal in breast cancer, with implications for therapeutic strategies.

bioRxiv · Oct 24, 2023 · PreprintCancer Biology

Exploration and analysis of molecularly annotated, 3D models of breast cancer at single-cell resolution using virtual reality

D. Bressan, C. M. Mulvey, F. Qosaj, R. Becker, F. Grimaldi, S. Coffey, S. L. Vogl, L. Kuett, R. Catena, A. Dariush, C. Gonzalez Fernandez, E. A. Gonzalez Solares, M. Al Sa'd, A. Küpkü Yoldas, T. Whitmarsh, , G. J. Hannon

The paper introduces Theia, a virtual reality platform for exploring 3D molecularly annotated cancer datasets, and provides breast cancer datasets for analysis.

bioRxiv · Jun 28, 2021 · PreprintCancer Biology

Compensatory CSF2-driven macrophage activation promotes adaptive resistance to CSF1R inhibition in breast-to-brain metastasis

F. Klemm, A. Schaeffer, A. Salamero-Boix, T. Alekseeva, M. Schulz, K. Niesel, R. R. Maas, M. Groth, B. T. Elie, R. L. Bowman, M. E. Hegi, R. T. Daniel, P. S. Zeiner, J. Zinke, P. N. Harter, , L. Sevenich

The paper shows that blocking CSF1R in brain metastases initially reduces tumor growth but is ineffective in established tumors due to compensatory macrophage activation, which is overcome by combining CSF1R and STAT5 inhibition.

bioRxiv · Jun 7, 2021Cancer Biology

A Carbon Nanotube Optical Reporter Maps Endolysosomal Lipid Flux

P. V. Jena, D. Roxbury, T. V. Galassi, L. Akkari, C. P. Horoszko, D. B. Iaea, J. Budhathoki-Uprety, N. H. Pipalia, A. S. Haka, J. D. Harvey, J. Mittal, F. R. Maxfield, J. A. Joyce, D. A. Heller

This paper develops an optical reporter using carbon nanotubes to measure endolysosomal lipid flux in live cells, revealing lipid accumulation in disease models and sub-cellular heterogeneity.

bioRxiv · Aug 28, 2017Bioengineering