Author

J. D. Tranter

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

E. E. Morrison· 2 shared J. W. Dear· 2 shared A. Lartigau· 1 shared A. Srivastava· 1 shared B. Lopez-Longarela· 1 shared C. Goldring· 1 shared D. C. Duffy· 1 shared D. M. Rissin· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPharmacology & Toxicology

E. E. Morrison

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2 papers

Recent·Most cited

Transfer of hepatocellular microRNA regulates cytochrome P450 2E1 in renal tubular cells

O. Matthews, E. E. Morrison, J. D. Tranter, P. Starkey Lewis, I. Toor, A. Srivastava, R. Sargeant, H. Rollison, K. P. Matchett, G. A. Gray, C. Goldring, K. Park, L. Denby, N. Dhaun, M. A. Bailey, , J. W. Dear

This study shows that hepatocyte-derived microRNA, particularly miR-122, is transferred to kidney tubular cells and regulates CYP2E1 expression, influencing drug toxicity.

bioRxiv · Jan 6, 2020Pharmacology & Toxicology

Direct detection of circulating microRNA-122 using dynamic chemical labelling with single molecule detection overcomes stability and isomiR challenges for biomarker qualification

B. Lopez-Longarela, E. E. Morrison, J. D. Tranter, L. Chahman-Vos, J.-F. Leonard, J.-C. Gautier, S. Laurent, A. Lartigau, E. Boitier, L. Sautier, P. Carmona-Saez, J. Martorell-Marugan, R. J. Mellanby, S. Pernagallo, H. Ilyine, , J. J. Diaz-Mochon

This paper develops a DCL assay to directly detect miR-122 in serum/plasma, overcoming stability and isomiR challenges for DILI biomarker qualification.

bioRxiv · Sep 20, 2019 · PreprintPharmacology & Toxicology