Author

K. P. Matchett

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

N. C. Henderson· 3 shared C. J. Weston· 2 shared J. R. Portman· 2 shared P. Ramachandran· 2 shared R. Dobie· 2 shared S. J. Wigmore· 2 shared A. Kapourani· 1 shared A. Srivastava· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

N. C. Henderson

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Multimodal decoding of human liver regeneration

K. P. Matchett, J. W. Wilson-Kanamori, J. R. Portman, A. Kapourani, F. Fercoq, S. May, J. B. Mackey, M. Brice, E. Zajdel, M. Beltran-Sierra, E. F. Sutherland, G. C. Wilson, S. J. Wallace, L. Kitto, N. T. Younger, , N. C. Henderson

This study uses single-nuclei RNA sequencing and spatial profiling to create a single-cell atlas of human liver regeneration, identifying a novel migratory hepatocyte subpopulation and demonstrating that wound closure precedes hepatocyte proliferation.

bioRxiv · Feb 24, 2023Cell Biology

Transfer of hepatocellular microRNA regulates cytochrome P450 2E1 in renal tubular cells

O. Matthews, E. E. Morrison, J. D. Tranter, P. Starkey Lewis, I. Toor, A. Srivastava, R. Sargeant, H. Rollison, K. P. Matchett, G. A. Gray, C. Goldring, K. Park, L. Denby, N. Dhaun, M. A. Bailey, , J. W. Dear

This study shows that hepatocyte-derived microRNA, particularly miR-122, is transferred to kidney tubular cells and regulates CYP2E1 expression, influencing drug toxicity.

bioRxiv · Jan 6, 2020Pharmacology & Toxicology

Resolving the fibrotic niche of human liver cirrhosis using single-cell transcriptomics

P. Ramachandran, R. Dobie, J. R. Wilson-Kanamori, E. F. Dora, B. E. Henderson, R. S. Taylor, K. P. Matchett, J. R. Portman, M. Efremova, R. Vento-Tormo, N. T. Luu, C. J. Weston, P. N. Newsome, E. M. Harrison, D. J. Mole, , N. C. Henderson

This study uses single-cell transcriptomics to identify novel fibrotic cell types and interactions in human liver cirrhosis, revealing potential therapeutic targets.

Nature · Oct 9, 2019Peer-reviewedImmunology