Author

B. R. Conklin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioengineering· 1 Biophysics· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Organism:human· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:clustering· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:imaging· 2

Frequent Co-Authors

J. A. Perez-Bermejo· 4 shared D. A. Joy· 2 shared P.-L. So· 2 shared T. C. McDevitt· 2 shared A. Bertero· 1 shared A. C. Silva· 1 shared A. H. Chan· 1 shared A. Kulkarni· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersCell Biology

J. A. Perez-Bermejo

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Gain-of-function cardiomyopathic mutations in RBM20 rewire splicing regulation and re-distribute ribonucleoprotein granules within processing bodies

A. M. Fenix, Y. Miyaoka, A. Bertero, S. Blue, M. J. Spindler, K. K. B. Tan, J. A. Perez-Bermejo, A. H. Chan, S. J. Mayer, T. Nguyen, C. R. Russell, P. Lizarraga, A. Truong, P.-L. So, A. Kulkarni, , N. Salomonis

This study investigates how RBM20 mutations affect splicing and ribonucleoprotein granules in cardiomyopathy, revealing distinct pathogenic mechanisms between missense and knockout mutations.

bioRxiv · Jun 2, 2021Cell Biology

Synchronization of iPS-derived cardiomyocytes to visitor heartbeat in an interactive museum exhibit

J. A. Perez-Bermejo, S. J. Reisman, J. Ma, C. Cerrito, B. R. Conklin, K. Yu

This paper describes an interactive museum exhibit that synchronizes live human cardiomyocytes to visitor heart rates, engaging the public with heart biology and stem cell science.

bioRxiv · Apr 19, 2021 · PreprintScientific Communication & Education

uPTI: uniaxial permittivity tensor imaging of intrinsic density and anisotropy

L.-H. Yeh, I. E. Ivanov, J. R. Byrum, B. B. Chhun, S.-M. Guo, C. Foltz, E. Hashemi, J. A. Perez-Bermejo, H. Wang, Y. Yu, P. G. Kazansky, B. R. Conklin, M. H. Han, S. B. Mehta

This paper introduces uPTI, a label-free imaging method to measure permittivity tensors in biological samples, enabling 3D orientation and symmetry analysis of cellular structures with high resolution.

bioRxiv · Dec 15, 2020 · PreprintBiophysics

SARS-CoV-2 infection of human iPSC-derived cardiac cells predicts novel cytopathic features in hearts of COVID-19 patients

J. A. Perez-Bermejo, S. S. Kang, S. J. Rockwood, C. R. Simoneau, D. A. Joy, G. N. Ramadoss, A. C. Silva, W. R. Flanigan, H. Li, K. Nakamura, J. D. Whitman, M. Ott, B. R. Conklin, T. C. McDevitt

This study infects human iPSC-derived cardiac cells with SARS-CoV-2 and identifies novel cytopathic features in COVID-19 patient hearts, including myofibrillar fragmentation and DNA loss in cardiomyocytes.

bioRxiv · Aug 25, 2020Cell Biology

Spatiotemporal mosaic patterning of pluripotent stem cells using CRISPR interference

A. R. G. Libby, D. A. Joy, P.-L. So, M. A. Mandegar, J. M. Muncie, V. M. Weaver, B. R. Conklin, T. C. McDevitt

This study uses CRISPR interference to create spatiotemporal patterns in hiPSC colonies, revealing how gene knockdowns affect multicellular organization and symmetry breaking during development.

bioRxiv · Jan 24, 2018Bioengineering