Author

S. J. Rockwood

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. C. Silva· 2 shared D. A. Joy· 2 shared G. N. Ramadoss· 2 shared T. C. McDevitt· 2 shared A. J. Samelson· 1 shared A. Mac Kain· 1 shared B. Conklin· 1 shared B. R. Conklin· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

A. C. Silva

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Author profile →

3 papers

Recent·Most cited

Cell BiologybioRxivJan 19, 2021

BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2

A. J. Samelson, Q. D. Tran, R. Robinot…·M. Kampmann

This study identifies BRD2 as a regulator of ACE2 transcription and shows that BRD2 inhibitors block SARS-CoV-2 infection in human cells and animal models.

DOI 10.1038/s41556-021-00821-8

humanmouse

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Cell BiologybioRxivAug 25, 2020

SARS-CoV-2 infection of human iPSC-derived cardiac cells predicts novel cytopathic features in hearts of COVID-19 patients

J. A. Perez-Bermejo, S. S. Kang, S. J. Rockwood…·T. C. McDevitt

This study infects human iPSC-derived cardiac cells with SARS-CoV-2 and identifies novel cytopathic features in COVID-19 patient hearts, including myofibrillar fragmentation and DNA loss in cardiomyocytes.

DOI 10.1126/scitranslmed.abf7872

humanbulk RNA-seq

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Cell BiologybioRxivPreprintJul 31, 2020

Cardiac Cell-Derived Matrices Impart Age-Specific Functional Properties to Human Cardiomyocytes

M. A. Kauss, S. J. Rockwood, A. C. Silva…·T. C. McDevitt

The paper develops a method to create stable cardiac cell-derived matrices and shows that fetal and adult matrices impart distinct functional properties to cardiomyocytes, with collagen VI in fetal matrices enhancing oxidative respiration.

DOI 10.1101/2020.07.31.231480

humanproteomics

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