Author

J. E. M. van der Lubbe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Organism:rat· 2 Research Focus:benchmarking· 1 Assay:protein structure· 1

Frequent Co-Authors

D. H. Barouch· 4 shared F. Wegmann· 4 shared H. Schuitemaker· 4 shared E. J. Snijder· 3 shared L. Dekking· 3 shared M. Kikkert· 3 shared R. C. Zahn· 3 shared S. K. Myeni· 3 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

D. H. Barouch

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Author profile →

4 papers

Recent·Most cited

ImmunologybioRxivJan 30, 2021

SARS-CoV-2 binding and neutralizing antibody levels after vaccination with Ad26.COV2.S predict durable protection in rhesus macaques

R. Roozendaal, L. Solforosi, D. Stieh…·R. Zahn

This study shows that Ad26.COV2.S vaccine provides long-lasting protection in rhesus macaques, predicted by binding and neutralizing antibody levels against SARS-CoV-2.

DOI 10.1038/s41467-021-26117-x

ratexperimental assay

𝕏 PostBluesky

ImmunologybioRxivPreprintJan 8, 2021

Ad26.COV2.S-elicited immunity protects against G614 spike variant SARS-CoV-2 infection in Syrian hamsters and does not enhance respiratory disease in challenged animals with breakthrough infection after sub-optimal vaccine dosing

J. E. M. van der Lubbe, S. K. Rosendahl Huber, A. Vijayan…·F. Wegmann

This study shows that a single dose of Ad26.COV2.S vaccine protects Syrian hamsters from G614 SARS-CoV-2 infection and prevents VAERD even with suboptimal immunity.

DOI 10.1101/2021.01.08.425915

mouseexperimental assay

𝕏 PostBluesky

ImmunologybioRxivNov 17, 2020

Immunogenicity and protective efficacy of one- and two-dose regimens of the Ad26.COV2.S COVID-19 vaccine candidate in adult and aged rhesus macaques

L. Solforosi, H. Kuipers, S. K. Rosendahl Huber…·R. C. Zahn

This study evaluates one- and two-dose regimens of the Ad26.COV2.S vaccine in rhesus macaques, showing higher antibody responses with two doses and protection against SARS-CoV-2 in aged animals.

DOI 10.1084/jem.20202756

ratexperimental assay

𝕏 PostBluesky

ImmunologybioRxivJul 30, 2020

Ad26-vector based COVID-19 vaccine encoding a prefusion stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses

R. Bos, L. Rutten, J. E. M. van der Lubbe…·H. Schuitemaker

This paper evaluates a prefusion-stabilized SARS-CoV-2 Spike protein vaccine candidate, Ad26.COV2.S, showing potent neutralizing and Th1-polarized immune responses in mice.

DOI 10.1038/s41541-020-00243-x

mouseprotein structure

𝕏 PostBluesky