J. E. Prier

KDM6B-dependent chromatin remodelling underpins effective virus-specific CD8+ T cell differentiation.

This study identifies KDM6B-dependent chromatin remodelling as critical for virus-specific CD8+ T cell differentiation and memory formation.

Development of a KDM6b shRNA conditional knock down mouse model

This paper develops a conditional KDM6b shRNA mouse model and shows that its knockdown reduces CD8+ T cell responses to influenza A infection without affecting T-BET expression.