Constitutive expression and distinct properties of IFN-epsilon protect the female reproductive tract from Zika virus infection
R. Coldbeck-Shackley, O. Romeo, S. Rosli, L. J. Gearing, J. A. Gould, S. S. Lim, K. Van der Hoek, N. S. Eyre, B. Shue, S. A. Robertson, S. M. Best, M. D. Tate, P. Hertzog, M. R. Beard
This paper shows that IFN-epsilon's constitutive expression in the female reproductive tract provides innate antiviral protection against Zika virus by resisting viral antagonism and enhancing antiviral activity.
PLOS Pathogens · Mar 10, 2023Peer-reviewedImmunology