Author

J. Elferich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:cryo-EM· 2 Approach:experimental assay· 2 Approach:microscopy & imaging analysis· 2 Research Focus:protein structure prediction· 2 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

E. Gouaux· 2 shared N. Grigorieff· 2 shared A. Goehring· 1 shared A. Matsui· 1 shared C. Spangler· 1 shared D. Scadden· 1 shared G. Schiroli· 1 shared H. Zhong· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBiochemistry

E. Gouaux

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cryo-electron tomographic investigation of native hippocampal glutamatergic synapses

A. Matsui, C. Spangler, J. Elferich, M. Shiozaki, N. Jean, X. Zhao, M. Qin, H. Zhong, Z. Yu, E. Gouaux

The paper develops methods to image glutamatergic synapses in hippocampal tissue using cryo-electron tomography, enabling high-resolution visualization of synaptic structures.

bioRxiv · Apr 1, 2024Biochemistry

CTFFIND5 provides improved insight into quality, tilt and thickness of TEM samples

J. Elferich, L. Kong, X. Zottig, N. Grigorieff

CTFFIND5 improves CTF estimation by incorporating sample thickness and tilt, enhancing cryoEM image quality assessment.

bioRxiv · Feb 26, 2024Biophysics

Single molecule studies of the native hair cell mechanosensory transduction complex

S. Clark, J. Mitra, J. Elferich, A. Goehring, J. Ge, T. Ha, E. Gouaux

This study optimizes single molecule assays to detect and quantify the native hair cell mechanosensory transduction complex at attomole levels.

bioRxiv · Dec 11, 2023 · PreprintBiochemistry

Defocus Corrected Large Area Cryo-EM (DeCo-LACE) for Label-Free Detection of Molecules across Entire Cell Sections

J. Elferich, G. Schiroli, D. Scadden, N. Grigorieff

The paper introduces DeCo-LACE, a cryo-EM method for whole-cell section imaging, and uses 2DTM to map ribosome locations, enhancing visual proteomics.

bioRxiv · Jun 13, 2022Cell Biology