Author

J. F. Gritzfeld

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. Solorzano· 2 shared E. L. German· 2 shared E. Mitsi· 2 shared E. Nikolaou· 2 shared A. D. Hyder-Wright· 1 shared A. Hyder-Wright· 1 shared A. M. Collins· 1 shared B. F. Carniel· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMicrobiology

C. Solorzano

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Author profile →

2 papers

Recent·Most cited

Efficacy of PCV vaccine is primarily mediated by controlling pneumococcal colonisation density

E. L. German, C. Solorzano, S. Sunny, F. Dunne, J. F. Gritzfeld, E. Mitsi, E. Nikolaou, A. D. Hyder-Wright, A. M. Collins, S. B. Gordon, D. Ferreira

This study re-evaluates PCV-13 efficacy using molecular methods, finding reduced colonisation acquisition and density, suggesting vaccine impact is primarily through controlling colonisation density.

bioRxiv · Feb 14, 2019 · PreprintMicrobiology

Inflammation induced by influenza virus impairs innate control of human pneumococcal carriage

S. P. Jochems, F. Marcon, B. F. Carniel, M. Holloway, E. Mitsi, E. Smith, J. F. Gritzfeld, C. Solorzano, J. Reine, S. Pojar, E. Nikolaou, E. L. German, A. Hyder-Wright, H. Hill, C. Hales, , D. M. Ferreira

This study shows that influenza virus infection impairs innate immune responses to pneumococcal carriage in the nose, increasing bacterial density through cytokine-driven mechanisms.

bioRxiv · Jun 20, 2018Immunology