Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
8 papers
Recent·Most cited
E. Mitsi, M. O. Diniz, J. Reine, A. M. Collins, R. Robinson, A. Hyder-Wright, M. Farrar, K. Liatsikos, J. Hamilton, O. Onyema, B. C. Urban, C. Solorzano, T. Lambe, S. J. Draper, D. Weiskopf, , D. M. Ferreira
This study shows that hybrid immunity from infection plus vaccination generates durable lung mucosal immunity, while peripheral vaccination alone does not.
bioRxiv · Jan 25, 2023 · PreprintImmunology
J. Reine, B. F. Carniel, C. Solorzano, E. Mitsi, S. Pojar, E. Nikolau, E. L. German, A. D. Hyder-Wright, H. Hill, C. Hales, L. Brown, V. Horsley, L. Hughes, S. Zaidi, V. Connor, , S. P. Jochems
This study examines age-related changes in nasal mucosal immune composition and function, finding reduced granulocytes and T cells in young children and older adults, and links pneumococcal colonization to inflammation.
bioRxiv · Mar 14, 2019 · PreprintImmunology
E. Nikolaou, A. Blizard, S. Pojar, E. Mitsi, E. L. German, J. Reine, H. Hill, P. S. McNamara, A. M. Collins, D. M. Ferreira, S. P. Jochems
This study shows that nasal lining fluid filter strips provide equal pneumococcal detection sensitivity to deep nasopharyngeal swabs in children, offering a less unpleasant alternative.
bioRxiv · Mar 13, 2019Microbiology
E. L. German, C. Solorzano, S. Sunny, F. Dunne, J. F. Gritzfeld, E. Mitsi, E. Nikolaou, A. D. Hyder-Wright, A. M. Collins, S. B. Gordon, D. Ferreira
This study re-evaluates PCV-13 efficacy using molecular methods, finding reduced colonisation acquisition and density, suggesting vaccine impact is primarily through controlling colonisation density.
bioRxiv · Feb 14, 2019 · PreprintMicrobiology
S. P. Jochems, K. de Ruiter, C. Solorzano, A. Voskamp, E. Mitsi, E. Nikolaou, B. F. Carniel, S. Pojar, E. German, J. Reine, A. Soares-Schanoski, H. Hill, R. Robinson, A. D. Hyder-Wright, C. Weight, , D. M. Ferreira
The paper uses mass cytometry to analyze nasal immune cells after pneumococcal challenge, identifying immune changes linked to colonization and host-pathogen interactions.
bioRxiv · Feb 11, 2019Immunology
E. Nikolaou, S. P. Jochems, E. Mitsi, S. Pojar, E. Negera, J. Reine, B. Carniel, A. Soares-Schanoski, V. Connor, H. Adler, S. R. Zaidi, C. Hales, H. Hill, A. Hyder-Wright, S. B. Gordon, , D. Ferreira
This study uses a human challenge model to show that nasal colonization by Streptococcus pneumoniae can take up to 24 hours and identifies two distinct clearance mechanisms involving neutrophils.
bioRxiv · Nov 5, 2018 · PreprintImmunology
S. P. Jochems, F. Marcon, B. F. Carniel, M. Holloway, E. Mitsi, E. Smith, J. F. Gritzfeld, C. Solorzano, J. Reine, S. Pojar, E. Nikolaou, E. L. German, A. Hyder-Wright, H. Hill, C. Hales, , D. M. Ferreira
This study shows that influenza virus infection impairs innate immune responses to pneumococcal carriage in the nose, increasing bacterial density through cytokine-driven mechanisms.
bioRxiv · Jun 20, 2018Immunology
J. Rylance, W. A. de Steenhuijsen Piters, S. Pojar, E. Nikolaou, E. German, E. Mitsi, S. Jochems, B. Carniel, C. Solorzano, J. Reine, J. Gritzfeld, M. L. J. Chu, K. Arp, A. D. Hyder-Wright, H. Hill, , D. M. Ferreira
This study tests if LAIV affects pneumococcal carriage in humans, finding transient increases in bacterial density but no overall change in acquisition rates.
bioRxiv · Jun 14, 2018Immunology