Author

J. Gouge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. Vannini· 2 shared C. Engel· 2 shared A. M. Vera· 1 shared D. Grohmann· 1 shared E. Morris· 1 shared E. P. Ramsay· 1 shared F. B. Heiss· 1 shared F. Beuron· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

A. Vannini

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Author profile →

2 papers

Recent·Most cited

Structure of human RNA Polymerase III

E. P. Ramsay, G. Abascal-Palacios, J. L. Daiss, H. King, J. Gouge, M. Pilsl, F. Beuron, E. Morris, P. Gunkel, C. Engel, A. Vannini

The paper determines the structure of human RNA Polymerase III using cryo-EM and maps mutations linked to neurodevelopmental disorders and viral hypersensitivity.

bioRxiv · Jun 29, 2020 · PreprintBiochemistry

DNA origami-based single-molecule force spectroscopy unravels the molecular basis of RNA Polymerase III pre-initiation complex stability

K. Kramm, T. Schroeder, J. Gouge, A. M. Vera, F. B. Heiss, T. Liedl, C. Engel, A. Vannini, P. Tinnefeld, D. Grohmann

The paper uses DNA origami force clamps to study how force affects initiation complex stability in RNA polymerase II and III systems, revealing Bdp1's critical role in RNAP III stability.

bioRxiv · Sep 19, 2019 · PreprintBiophysics