Author

J. L. Daiss

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:differential expression· 2 Assay:structural biology· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:clinical cohort / trial· 1

Frequent Co-Authors

A. Vannini· 2 shared C. Engel· 2 shared G. Abascal-Palacios· 2 shared M. Pilsl· 2 shared A. Bleckmann· 1 shared A. Bruckmann· 1 shared A. Derrico· 1 shared A. M. Franchini· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBiochemistry

A. Vannini

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The human RNA polymerase I structure reveals an HMG-like transcription factor docking domain specific to metazoans

J. L. Daiss, M. Pilsl, K. Straub, A. Bleckmann, M. Höcherl, F. B. Heiss, G. Abascal-Palacios, E. Ramsay, K. Tluckova, J.-C. Mars, A. Bruckmann, C. Bernecky, V. Lamour, K. Panov, A. Vannini, , C. Engel

The paper determines the structure of human RNA polymerase I, identifies a novel HMG-like domain in RPA1, and shows its role in recruiting Topoisomerase 2a and UBF for transcription regulation.

bioRxiv · Dec 22, 2021 · PreprintBiochemistry

Biphasic effects of IL-27 during Staphylococcus aureus implant-associated osteomyelitis in mice

Y. Morita, A. M. Franchini, J. R. Owen, J. C. Martinez, J. L. Daiss, K. L. de Mesy Bentley, S. L. Kates, E. M. Schwarz, G. Muthukrishnan

This study identifies IL-27 as a biphasic cytokine with proinflammatory and anti-inflammatory roles during S. aureus osteomyelitis, suggesting it as a therapeutic target.

bioRxiv · May 20, 2021 · PreprintImmunology

Elevated SARS-CoV-2 Antibodies Distinguish Severe Disease in Early COVID-19 Infection

N. S. Haddad, D. C. Nguyen, M. E. Kuruvilla, A. Morrison-Porter, F. Anam, K. S. Cashman, R. P. Ramonell, S. Kyu, A. S. Saini, M. Cabrera-Mora, A. Derrico, D. Alter, J. D. Roback, M. Horwath, J. B. O'Keefe, , F. E.-H. Lee

This paper develops a multiplex immunoassay to measure SARS-CoV-2 antibody responses and finds that severe COVID-19 is associated with higher early antibody levels against S1 and N proteins.

bioRxiv · Dec 4, 2020 · PreprintImmunology

Structure of human RNA Polymerase III

E. P. Ramsay, G. Abascal-Palacios, J. L. Daiss, H. King, J. Gouge, M. Pilsl, F. Beuron, E. Morris, P. Gunkel, C. Engel, A. Vannini

The paper determines the structure of human RNA Polymerase III using cryo-EM and maps mutations linked to neurodevelopmental disorders and viral hypersensitivity.

bioRxiv · Jun 29, 2020 · PreprintBiochemistry