Discovery of a hidden transient state in all bromodomain families
L. Raich, K. Meier, J. Günther, C. D. Christ, F. Noe, S. Olsson
The paper identifies a transient state in all bromodomain families using molecular dynamics simulations and structural data, suggesting it acts as an allosteric regulatory switch.
bioRxiv · Apr 1, 2020Biophysics