S. Olsson

Rescuing Off-Equilibrium Simulation Data through Dynamic Experimental Data with dynAMMo

The paper introduces dynAMMo, a method that combines MD simulations and experimental data to model protein dynamics on long timescales, overcoming limitations of both approaches.

Resilience of genetic diversity in forest trees over the Quaternary

The paper uses population genomic analyses to show that forest trees maintained genetic diversity despite Pleistocene climate changes.

Transcriptome analysis of protein kinase MoCK2 affect acetyl-CoA metabolism and import of CK2 interacting mitochondrial proteins into mitochondria in rice blast fungus Magnaporthe oryzae

This paper investigates the role of MoCK2 in rice blast fungus metabolism and mitochondrial protein import, finding it affects acetyl-CoA production and mitochondrial function essential for pathogenesis.

The wheat head blight pathogen Fusarium graminearum recruits facultative endohyphal bacteria from the soil, making the fungal-bacterial holobiont nitrogen-fixing and increasing the fungal pathogenicity

This study shows that the wheat pathogen Fusarium graminearum can acquire nitrogen-fixing facultative endohyphal bacteria from soil, enhancing its pathogenicity.

Whole genome regulatory effect of MoISW2 and consequences for the evolution of rice plant pathogenic fungus Magnaporthe oryzae

The paper investigates the regulatory role of MoISW2 in Magnaporthe oryzae, showing its impact on gene expression variability and niche-determinant genes, with implications for fungal evolution.

The Myb family genes in the rice pathogen Magnaporthe oryzae: Finding and deleting more family members involved in pathogenicity

The paper identifies and deletes 19 Myb genes in Magnaporthe oryzae, finds most are expressed during infection, and identifies co-regulated groups with potential roles in pathogenicity.

Molecular mechanism of SARS-CoV-2 cell entry inhibition via TMPRSS2 by Camostat and Nafamostat mesylate

This study investigates how camostat and nafamostat inhibit SARS-CoV-2 entry by targeting TMPRSS2 through molecular simulations and experiments, showing nafamostat's higher efficacy due to increased Michaelis complex binding.

A novel microcosm for recruiting inherently competitive biofertilizer-candidate microorganisms from soil environments

This paper develops a soil microcosm to isolate microorganisms capable of degrading precipitated phytate, showing recruitment of specific bacterial taxa and enzyme activity.

Evolutionary conserved multifunctional nitric oxide synthesis proteins responding to bacterial MAMPs are located at the endoplasmic reticulum

The paper identifies an evolutionary conserved NO-producing system in fungi, mammals, and plants, revealing multifunctional enzymes with implications for agriculture and medicine.

The Ceratodon purpureus genome uncovers structurally complex, gene rich sex chromosomes

The paper compares genomes of male and female mosses to study sex chromosome evolution, finding gene-rich, non-degenerated UV sex chromosomes.

Discovery of a hidden transient state in all bromodomain families

The paper identifies a transient state in all bromodomain families using molecular dynamics simulations and structural data, suggesting it acts as an allosteric regulatory switch.

OmicsDB::Pathogens - A database for exploring functional networks of plant pathogens

OmicsDB::Pathogens provides a platform for exploring genomic and gene co-expression networks of plant pathogens and reference species to generate hypotheses about gene function.

Protein interactions of Magnaporthe oryzae protein kinase CK2 and secondary data analysis of a large number of transcriptomes suggest chaperone-like activity is integral to its function

The paper identifies CK2 interacting proteins in M. oryzae and shows CK2 correlates with phosphatases and disaggregases, suggesting a role in protein aggregation and RNA/DNA binding.

Reckless driving: Improved phosphorous availability is a most likely important driver and species killer in angiosperm evolution

The paper investigates the relationship between phosphorous availability and genome size in angiosperms, suggesting that improved phosphorous status likely drives genome expansion and that P-limitation restricts evolution.

Magnaporthe oryzae CK2 is involved in rice blast pathogenesis and accumulates in nuclei, nucleoli, at septal and appressoria pores and forms a large ring structure in appressoria

This study investigates the localization and role of CK2 in Magnaporthe oryzae during growth and infection, finding it localizes to nuclei, nucleoli, septal pores, and appressoria with regulatory functions.

Dynamic Graphical Models of Molecular Kinetics

This paper introduces Dynamic Graphical Models (DGMs) to describe molecular kinetics and thermodynamics, showing they can predict new metastable states with fewer parameters than traditional methods.

The effect of community dialogues and sensitization on patient reporting of adverse events in rural Uganda: uncontrolled before-after study

This study evaluates the impact of a community engagement strategy on adverse drug event reporting in rural Uganda, finding increased awareness and reporting rates after the intervention.