Author

I. Gaspar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Organism:Drosophila· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Ephrussi· 4 shared S. Heber· 2 shared A. Komissarov· 1 shared B. J. H. Dequeker· 1 shared D. Niessing· 1 shared F. Wippich· 1 shared H. B. Brandao· 1 shared I. F. Davidson· 1 shared

Activity by Year

2016-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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4 shared papersCell Biology

A. Ephrussi

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

An RNA-based feed-forward mechanism ensures motor switching in oskar mRNA transport

I. Gaspar, L. J. Phea, M. A. McClintock, S. Heber, S. L. Bullock, A. Ephrussi

The paper shows that Staufen and Egl interact to switch motor proteins during oskar mRNA transport in Drosophila oocytes, enabling proper localization.

bioRxiv · Apr 24, 2021 · PreprintCell Biology

MCM complexes are barriers that restrict cohesin-mediated loop extrusion

B. J. H. Dequeker, H. B. Brandao, M. J. Scherr, J. Gassler, S. Powell, I. Gaspar, I. M. Flyamer, W. Tang, R. Stocsits, I. F. Davidson, J.-M. Peters, K. E. Duderstadt, L. A. Mirny, K. Tachibana

The paper shows MCM complexes block cohesin-mediated loop extrusion, reducing CTCF-anchored loops and TAD boundary insulation in G1 phase.

bioRxiv · Oct 15, 2020Cell Biology

Staufen2 mediated RNA recognition and localization requires combinatorial action of multiple domains

S. Heber, I. Gaspar, J.-N. Tants, J. Günther, S. M. Fernandez Moya, R. Janowski, A. Ephrussi, M. Sattler, D. Niessing

This study shows that dsRBDs 1-2 of mStau2 are essential for mRNA recognition and function, as demonstrated by rescue experiments in Drosophila oocytes.

bioRxiv · Feb 1, 2019Biochemistry

Enzymatic production of single molecule FISH and RNA capture probes

I. Gaspar, F. Wippich, A. Ephrussi

The paper describes a method to label DNA oligonucleotides with fluorescent dyes or biotin using terminal deoxynucleotidyl transferase, enabling single molecule FISH and RNA capture.

bioRxiv · Feb 10, 2017Cell Biology

An RNA-binding tropomyosin recruits kinesin-1 dynamically to oskar mRNPs

I. Gaspar, V. Sysoev, A. Komissarov, A. Ephrussi

The paper shows that DmTropomyosin1-I/C recruits kinesin-1 to oskar mRNPs dynamically during oogenesis, with motor activation linked to spliced RNA elements.

bioRxiv · Aug 4, 2016Cell Biology