Author

J. H. Rowe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Organism:mouse· 1

Frequent Co-Authors

J. Jacob· 2 shared K. S. Carmon· 2 shared S. Subramanian· 2 shared Z. Liang· 2 shared A. Azhdarinia· 1 shared C. Guernsey-Biddle· 1 shared H. Tran· 1 shared K. Tsuchikama· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersCancer Biology

J. Jacob

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer

J. Jacob, Y. Anami, P. High, Z. Liang, S. Subramanian, S. C. Ghosh, S. AghaAmiri, C. Guernsey-Biddle, H. Tran, J. H. Rowe, A. Azhdarinia, K. Tsuchikama, K. S. Carmon

This study develops and tests EREG-targeting ADCs showing efficacy in both RAS mutant and wildtype CRC, with high potency and safety in preclinical models.

bioRxiv · Feb 20, 2024 · PreprintCancer Biology

An antibody-drug conjugate targeting GPR56 demonstrates efficacy in preclinical models of colorectal cancer

J. Jacob, L. E. Francisco, T. Chatterjee, Z. Liang, S. Subramanian, Q. J. Liu, J. H. Rowe, K. S. Carmon

This study develops an antibody-drug conjugate targeting GPR56 and shows it is effective against colorectal cancer models.

bioRxiv · Aug 11, 2022Cancer Biology