Ref-1/APE1 inhibition with novel small molecules blocks ocular neovascularization
S. P. Sheik Pran Babu, K. Sishtla, R. S. Sulaiman, B. Park, T. Shetty, F. Shah, M. L. Fishel, J. H. Wikel, M. R. Kelley, T. W. Corson
This paper develops and tests new Ref-1/APE1 inhibitors, showing they block ocular neovascularization in vitro, ex vivo, and in a mouse model.
bioRxiv · Jun 23, 2018Pharmacology & Toxicology