Author

M. R. Kelley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

B. Park· 1 shared F. Shah· 1 shared J. H. Wikel· 1 shared J. J. Ziarek· 1 shared J. Meng· 1 shared J. Z. Vilseck· 1 shared K. Sishtla· 1 shared M. L. Fishel· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPharmacology & Toxicology

B. Park

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2 papers

Recent·Most cited

Chemically induced partial unfolding of the multifunctional Apurinic/apyrimidinic endonuclease 1

R. Rai, O. Dawodu, J. Meng, S. M. Johnson, J. Z. Vilseck, M. R. Kelley, J. J. Ziarek, M. M. Georgiadis

This study investigates how the redox inhibitor APX3330 induces reversible partial unfolding of APE1, revealing structural changes relevant to its redox function.

Protein Science · May 15, 2025Peer-reviewedBiochemistry

Ref-1/APE1 inhibition with novel small molecules blocks ocular neovascularization

S. P. Sheik Pran Babu, K. Sishtla, R. S. Sulaiman, B. Park, T. Shetty, F. Shah, M. L. Fishel, J. H. Wikel, M. R. Kelley, T. W. Corson

This paper develops and tests new Ref-1/APE1 inhibitors, showing they block ocular neovascularization in vitro, ex vivo, and in a mouse model.

bioRxiv · Jun 23, 2018Pharmacology & Toxicology