Pharmacology & ToxicologybioRxiv
Ref-1/APE1 inhibition with novel small molecules blocks ocular neovascularization
S. P. Sheik Pran Babu, K. Sishtla, R. S. Sulaiman…·T. W. Corson
This paper develops and tests new Ref-1/APE1 inhibitors, showing they block ocular neovascularization in vitro, ex vivo, and in a mouse model.
DOI 10.1124/jpet.118.248088