Author

J. Houston

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

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Organism:C. elegans· 4 Approach:experimental assay· 4 Research Focus:chromatin & epigenetic regulation· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Approach:biophysical modeling· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Desai· 3 shared K. Oegema· 3 shared A. Deep· 2 shared K. D. Corbett· 2 shared P. Lara-Gonzalez· 2 shared T. Kim· 2 shared A. Gerson-Gurwitz· 1 shared A. K. Shiau· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersCell Biology

A. Desai

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4 papers

Recent·Most cited

Phospho-KNL-1 recognition by a TPR domain targets the BUB-1/BUB-3 complex to C. elegans kinetochores

J. Houston, C. Vissotsky, A. Deep, H. Hakozaki, E. Crews, K. Oegema, K. D. Corbett, P. Lara-Gonzalez, T. Kim, A. Desai

This study shows that the BUB-1 TPR domain directly binds phosphorylated KNL-1 motifs, essential for BUB-1-BUB-3 localization and function in C. elegans.

bioRxiv · Feb 9, 2024 · PreprintCell Biology

PLK-1 tethered on BUB-1 directs CDC-20 kinetochore recruitment to ensure timelyembryonic mitoses

J. Houston, M. Ohta, J. S. Gomez-Cavazos, A. Deep, K. D. Corbett, K. Oegema, P. Lara-Gonzalez, T. Kim, A. Desai

This study shows that PLK-1 tethered on BUB-1 promotes CDC-20 recruitment to kinetochores, ensuring timely mitosis in C. elegans embryos through phosphoregulation.

bioRxiv · Oct 7, 2022Cell Biology

BUB-1 and CENP-C Recruit PLK-1 to Control Chromosome Alignment and Segregation During Meiosis I in C. elegans Oocytes

S. J. P. Taylor, L. Bel Borja, F. Soubigou, J. Houston, D. K. Cheerambathur, F. Pelisch

This study identifies BUB-1 and CENP-C as recruiters of PLK-1 during meiosis I in C. elegans oocytes, revealing their roles in chromosome alignment and segregation.

bioRxiv · Oct 7, 2022Cell Biology

The N-terminal Tail of C. elegans CENP-A Interacts with KNL-2 and is Essential for Centromeric Chromatin Assembly

C. de Groot, J. Houston, B. Davis, A. Gerson-Gurwitz, J. Monen, K. Oegema, A. K. Shiau, A. Desai

This study identifies the N-terminal tail of C. elegans CENP-A as essential for centromeric chromatin assembly through its interaction with KNL-2, compensating for the absence of Scm3/HJURP.

bioRxiv · Dec 28, 2020Cell Biology