Favipiravir strikes the SARS-CoV-2 at its Achilles heel, the RNA polymerase
A. Shannon, B. Selisko, T.-T.-N. Le, J. Huchting, F. Touret, G. Piorkowski, V. Fattorini, F. Ferron, E. Decroly, C. Meier, B. Coutard, O. Peersen, B. Canard
This study shows Favipiravir inhibits SARS-CoV-2 by targeting its RNA polymerase through chain termination, slowed synthesis, and mutagenesis.
bioRxiv · May 15, 2020 · PreprintBiochemistry