Author

J. J. Yerbury

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

L. McAlary· 2 shared A. K. Walker· 1 shared D. Cox· 1 shared D. N. Saunders· 1 shared G. S. Wright· 1 shared H. Ecroyd· 1 shared I. A. Lambert-Smith· 1 shared L. Ooi· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

L. McAlary

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

High-content analysis of proteostasis capacity in cellular models of amyotrophic lateral sclerosis (ALS)

I. A. Lambert-Smith, J. J. Yerbury, D. N. Saunders

This paper develops a high-content analysis assay using destabilized firefly luciferase mutants to assess proteostasis disruption in ALS cell models, showing reduced chaperone network activity in SOD1A4V-expressing cells.

bioRxiv · Sep 23, 2021Cell Biology

A copper chaperone-mimetic polytherapy for SOD1-associated amyotrophic lateral sclerosis

L. McAlary, V. K. Shephard, G. S. Wright, J. J. Yerbury

This study shows that combining CuATSM and ebselen reduces SOD1 aggregation and cell death in a cell model of ALS.

bioRxiv · Feb 22, 2021 · PreprintBiochemistry

Neurodegenerative disease-associated protein aggregates are poor inducers of the heat shock response in neuronal-like cells

R. San Gil, D. Cox, L. McAlary, T. Berg, A. K. Walker, J. J. Yerbury, L. Ooi, H. Ecroyd

This study shows that neurodegenerative disease-associated protein aggregates fail to induce the heat shock response in neuronal-like cells, unlike non-pathogenic aggregation-prone proteins.

bioRxiv · Jan 6, 2020Cell Biology