Author

J. L. Stout

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Approach:experimental assay· 2 Assay:proteomics· 2 Organism:human· 1 Assay:metagenomics· 1 Organism:non-human primate· 1 Organism:rat· 1

Frequent Co-Authors

A. L. Marcinkiewicz· 3 shared A. P. Dupuis· 3 shared Y.-P. Lin· 3 shared A. D. Davis· 2 shared A. T. Ciota· 2 shared K. Strle· 2 shared M. A. Diuk-Wasser· 2 shared S.-O. Kolokotronis· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersMicrobiology

A. L. Marcinkiewicz

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Structural evolution of an immune evasion determinant shapes Lyme borreliae host tropism

A. L. Marcinkiewicz, K. Brangulis, A. P. Dupuis, T. M. Hart, M. Zamba_Campero, T. A. Nowak, J. L. Stout, I. Akopjana, A. Kazaks, J. Bogans, A. T. Ciota, P. Kraiczy, S.-O. Kolokotronis, Y.-P. Lin

This paper identifies a minor sequence variation in the CspZ protein of Borrelia burgdorferi that influences host-specific complement evasion and infectivity through FH-binding interface differences.

bioRxiv · Sep 13, 2022 · PreprintMicrobiology

Phylogenomic diversity elucidates mechanistic insights into Lyme borreliae host association

M. A. Combs, A. L. Marcinkiewicz, A. P. Dupuis, A. D. Davis, P. Lederman, T. A. Nowak, J. L. Stout, K. Strle, V. Fingerle, G. Margos, A. T. Ciota, M. A. Diuk-Wasser, S.-O. Kolokotronis, Y.-P. Lin

This study investigates how genetic variation in Lyme disease-causing Borrelia burgdorferi strains relates to their ability to evade host complement immune responses, revealing host-specific complement-evasion phenotypes.

bioRxiv · May 25, 2022Microbiology

Host specialization in microparasites transmitted by generalist vectors: insights into the cellular and immunological mechanisms

Y.-P. Lin, D. M. Tufts, A. P. Dupuis, M. Combs, A. L. Marcinkiewicz, A. D. Hirsbrunner, A. J. Diaz, J. L. Stout, A. M. Blom, K. Strle, A. D. Davis, L. D. Kramer, M. A. Diuk-Wasser

This study investigates host specialization in Lyme disease bacteria by testing different genotypes in reservoir hosts, finding that bacterial persistence depends on adhesion and immune evasion traits.

bioRxiv · Nov 13, 2020 · PreprintMicrobiology