K. Brangulis

Enhancement of clinical signs in C3H/HeJ mice vaccinated with a highly immunogenic Leptospira methyl-accepting chemotaxis protein following challenge

This study evaluates a recombinant Leptospira methyl-accepting chemotaxis protein (MCP) vaccine in C3H/HeJ mice, finding it elicits an immune response but does not prevent disease and may exacerbate clinical signs.

Structural evolution of an immune evasion determinant shapes Lyme borreliae host tropism

This paper identifies a minor sequence variation in the CspZ protein of Borrelia burgdorferi that influences host-specific complement evasion and infectivity through FH-binding interface differences.