J. M. B. Pineda

This study identifies DUX4 as a common driver of immune evasion and immunotherapy failure in metastatic cancers, associated with poor prognosis and resistance to PD-L1 blockade.

This study identifies aberrant MYB complex assembly as a driver of oncogenic gene expression in AML and shows that targeting this complex can induce differentiation and apoptosis.

The paper shows that a mutation increasing hypoxanthine release in yeast was mistakenly thought to be win-win but is actually self-serving due to increased cell size and lysine consumption.

The paper identifies and resolves challenges in modeling microbial community dynamics by re-measuring strain phenotypes in community-like environments.