Author

J. M. Skerker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Evolutionary Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 2 Organism:yeast· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. P. Arkin· 2 shared R. B. Brem· 2 shared A. A. Caudy· 1 shared B. T. Hovde· 1 shared C. A. Dubin· 1 shared C. Payen· 1 shared D. S. Clark· 1 shared D. Sivanandan· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBioengineering

A. P. Arkin

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Author profile →

3 papers

Recent·Most cited

Acetaminophen production in the edible, filamentous cyanobacterium Arthrospira platensis

J. M. Hilzinger, S. Friedline, D. Sivanandan, Y.-F. Cheng, S. Yamazaki, D. S. Clark, J. M. Skerker, A. P. Arkin

This paper develops a genetic toolkit for Arthrospira platensis and demonstrates acetaminophen production as a proof-of-concept for small molecule synthesis in an edible cyanobacterium.

bioRxiv · Jun 30, 2022 · PreprintBioengineering

Barcoded reciprocal hemizygosity analysis via sequencing illuminates the complex genetic basis of yeast thermotolerance

M. B. Abrams, J. N. Chuong, F. AlZaben, C. A. Dubin, J. M. Skerker, R. B. Brem

The paper improves RH-seq by adding barcodes for efficient sequencing, then uses it to identify thermotolerance-related loci in yeast species divergence.

G3 · Dec 8, 2021Peer-reviewedEvolutionary Biology

Transposon insertional mutagenesis in Saccharomyces uvarum reveals trans-acting effects influencing species dependent essential genes

M. R. Sanchez, C. Payen, F. Cheong, B. T. Hovde, S. Bissonnette, A. P. Arkin, J. M. Skerker, R. B. Brem, A. A. Caudy, M. J. Dunham

This study uses transposon mutagenesis in Saccharomyces uvarum to identify species-dependent essential genes and shows that trans-acting factors influence gene essentiality despite cross-species complementation.

Genome Research · Mar 1, 2019Peer-reviewedGenomics