Author

S. Friedline

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. P. Liu· 2 shared A. S. Helms· 2 shared Y.-C. Tsan· 2 shared A. Capilnasiu· 1 shared A. P. Arkin· 1 shared A. S. Dobbs· 1 shared B. Elder· 1 shared B. M. Baker· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

A. P. Liu

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Author profile →

3 papers

Recent·Most cited

Acetaminophen production in the edible, filamentous cyanobacterium Arthrospira platensis

J. M. Hilzinger, S. Friedline, D. Sivanandan, Y.-F. Cheng, S. Yamazaki, D. S. Clark, J. M. Skerker, A. P. Arkin

This paper develops a genetic toolkit for Arthrospira platensis and demonstrates acetaminophen production as a proof-of-concept for small molecule synthesis in an edible cyanobacterium.

bioRxiv · Jun 30, 2022 · PreprintBioengineering

Biomechanics and Myofibrillar Alignment Enhance Contractile Development and Reproducibility in Stem Cell Derived Cardiac Muscle

Y.-C. Tsan, Y.-T. Zhao, S. J. DePalma, A. Capilnasiu, Y.-W. Wu, B. Elder, I. Panse, S. Friedline, T. S. O'Leary, N. Wubshet, K. K. Y. Ho, M. J. Previs, D. Nordsletten, B. M. Baker, L. L. Isom, , A. S. Helms

This study develops a 2D platform to enhance contractile development and reproducibility in stem cell-derived cardiac muscle by controlling biomechanics and myofibrillar alignment.

bioRxiv · May 23, 2021 · PreprintCell Biology

Myofibrillar Structural Variability Underlies Contractile Function in Stem Cell-Derived Cardiomyocytes

K. Ufford, S. Friedline, Z. Tong, V. T. Tang, A. S. Dobbs, Y.-C. Tsan, S. L. Bielas, A. P. Liu, A. S. Helms

This study shows myofibrillar structure variability in iPSC-derived cardiomyocytes affects contractile function and should be considered in disease modeling and drug testing.

bioRxiv · Oct 13, 2020Cell Biology